Obesity Satiety center

Methamphetamine hydrochloride is an amphetamine that activates noradrenergic neurons causing CNS and respiratory stimulation and stimulates the satiety center in the brain, causing appetite suppression. It is indicated for treatment of attention deficit disorder in children it is a shortterm exogenous obesity adjunct. 

Sibutramine hydrochloride is an anorexiant that inhibits reuptake of norepinephrine, serotonin and dopamine. It may stimulate the satiety center in brain, causing appetite suppression. It is indicated as an adjunct to a reduced calorie diet for the management of obesity, including weight loss and maintenance of weight loss. Recommended for patients with an initial body mass index greater than 30 kg/m2 or greater than 27 kg/m in the presence of other risk factors (e.g., hypertension, diabetes, dyslipidemia). 

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