Nutritional genomics

DELLAPENNA D (1999) Nutritional genomics manipulating plant micronutrients to improve human health. Science. 285 375-9. 

Kaput, J., Rodriguez, R.L. (2004) Nutritional genomics the next frontier in the postgenomic era. Physiol. Genomics, 16,166-177. 

Miggiano G. A. D. and De Sanctis R. (2006). Nutrigenomica verso una dieta personalizzata [Nutritional genomics toward a personalized diet], Clin. Ter. 157 355-361. 

Although the human genome project and subsequent efforts have sparked interest in the effects of SNPs on common diseases, the intersection of genomics and nutrition is relatively unexplored. To this end, nutritional genomics has emerged as a discipline that seeks to provide information on gene-nutrient interactions (and vice... 

Vakili S, Caudill MA. Personalized nutrition Nutritional genomics as a potential tool for targeted medical nutrition therapy. NutrRev. 2007, 65 301-315. 

Guillermo Reglero, Molecular Oncology and Nutritional Genomics of Cancer, IMDEA Food Institute CEI UAM+CSIC, and Instituto de Investigation en Ciencias de la Alimentation (CIAL), CEI UAM+CSIC, Madrid, Spain... 

Kaput J, Rodriguez RL. Nutritional genomics The next frontier in the post-genomic era. Physiol Genomics 2004 16(2) 166-77. 

There s not much chance that nutritional genomics will ruin the pharmaceutical industry. Rather, the field has been creating opportunities for drug companies to isolate, concentrate, synthesize, and improve on the compounds in nature, as drug entrepreneurs have been doing for a hundred years. 

The use of the new functional genomic approaches in nutrition research, so-called nutritional genomics, presents the possibility for an entirely new approach that seeks to develop a global view of the biological effects of food [4, 5]. This approach, in which the ultimate aim is to examine all genes and cellular pathways simultaneously in complex organisms, is sometimes termed systems biology. 

Nutritional genomics is defined here as the application of all or any structural and functional genomic information/techniques within nutrition research. 

The beginning chapters of this volume are devoted to aspects of phytochemical research that are fundamental to this new era of activity. Chapter 1 introduces the fundamentals of nutritional genomics (nutrigenomics), notably DNA arrays, proteomics, and metabolomics, while Chapter 2 indicates the manifold factors affecting bioavailability, critically compares various methods for its measurement, and highlights crucial differences between studies on new drug formulations and dietary phytochemicals. The fundamental importance of considering metabolic processes is addressed in Chapter 3, with particular attention to those associated with the ubiquitous polyphenols. 

Table 1.1 Nutritional Genetics vs. Nutritional Genomics What Is Nutritional Genomics ...

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