Nucleophilic Substitution Hydrolytic Reactions of Halogenated Alkanes and Alkanoates

Nucleophilic Substitution Hydrolytic Reactions of Halogenated Alkanes and Alkanoates 

Displacement of halogen by hydroxyl is a widely distributed reaction in the degradation of halo-alkanes and haloalkanoates. Although an apparently simple pathway involving two displacement 

FIGURE 7.60 Degradation of methylene chloride by Dehalobacterium formicoaceticum. (From Neilson, A.H. and Allard, A.-S., The Handbook of Environmental Chemistry, Vol. 3R, pp. 1-74, Springer, 2002. With permission.) 

Specific Activity (pmol bromide produced/mg protein/min) of Dehalogenase from Selected Species of Mycobacterium towards 1,2-Dibromoethane 

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