Notebook synthesis experiment

In a synthesis experiment, the point of the exercise is to prepare a clean sample of the product you want. All the operations in the lab (e.g., distillation, recrystallization) are just means to this end. The preparation of 1-bromobutane is a classic synthesis and is the basis of the next series of handwritten notebook pages. 

The future of total synthesis is written in our laboratory notebooks. It will not only be conditioned by new synthetic achievements and new methodologies and technologies improving the efficacy of experiments but also by their applications to answer questions from new horizons. All of us will agree, as it was said by others, that total synthesis is marked by beauty and it has sometimes been compared with art. Not so many fields can respond to such criteria, and it is due to the free creativity we are able to exert. In theory, total synthesis could provide any compound, from the simplest to the most complex ones. But can we provide enough material for deepened studies in other research fields [52] Indeed, our products, once achieved, are not to be stored indefinitely in tiny flasks. They should lead to new projects, new questions, and new answers. 

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