Nortriptyline Propoxyphene

Clinically important, potentially hazardous interactions with amitriptyline, amoxapine, amphetamines, bupropion, citalopram, clomipramine, cyproheptadine, desipramine, dextroamphetamine, dextromethorphan, diethylpropion, dopamine, doxepin, entacapone, ephedra, ephedrine, epinephrine, fluoxetine, fluvoxamine, ginseng, imipramine, levodopa, mazindol, meperidine, methamphetamine, nefazodone, nortriptyline, paroxetine, phendimetrazine, phentermine, phenylephrine, pizotifen, propoxyphene, protriptyline, pseudoephedrine, rizatriptan, sertraline, sibutramine, sumatriptan, sympathomimetics, tramadol, tricyclic antidepressants, trimipramine, tryptophan, venlafaxine, zolmitriptan... [Pg.454]

Barbiturates and heavy smoking induce nortriptyline metabolism and decrease therapeutic efficacy phenothiazines and haloperidol decrease its metabolism, decreasing therapeutic efficacy methylphenidate, cimetidine, oral contraceptives, propoxyphene, and beta-blockers may inhibit nortriptyline metabolism, increasing plasma levels and toxicity (see Tables 5 through 7). [Pg.507]

Simultaneous N-acetylprocainamide, amoxapine, amphetamine, buprion, chlordiazepoxide, chlorpheniramine, chlorpromazine, cocaine, codeine, demoxepam, desipramine, desmethylchlordiazepoxide, desmethyldisop5rramide, desmethyldoxepin, dextropropoxy-phene, diazepam, disopyramide, fluphenazine, 2-hydroxydesipramine, 2-hydroxyimipramine, lO-hydroxynortriptyline, iminostilbene, imipramine, iprindole, loxepin, maprotiline, methadone, mianserin, morphine, nortriptyline, norzimeldine, oxapam, oxaprotiline, procainamide, prochlorperazine, prolixin, promethazine, propoxyphene, protriptyline, pjTi-lamine, trifluoperazine, trimeprazine, trimipramine, zimeldine... [Pg.69]

Simultaneous chlorpromazine, desipramine, desmethyldoxepin, disopyramide, doxepin, imipramine, maprotiline, nortriptyline, procainamide, propoxyphene, propranolol, thioridazine, trimipramine... [Pg.72]

Extracted amphetamine, benzoylecgonine, cocaine (different gradient), codeine, diphenhydramine (different gradient), ephedrine (different gradient), lidocaine (different gradient), meperidine, morphine, nordiazepam, phenylpropanolamine (different gradient), nor-propoxyphene, nortriptyline (different gradient)... [Pg.83]

Wong, S.H.Y. McHugh, S.L. Dolan, J. Cohen, K.A. Tricyclic antidepressant analysis by reversed-phase liquid chromatography using phenyl columns. J.Liq.Chromatogr., 1986, 9, 2511-2538 [also acetaminophen, amobarbital, amoxapine, barbital, chlordiazepoxide, chlorpromazine, cimetidine, clomipramine, codeine, desipramine, desmethyldoxepin, diazepam, doxepin, fluphenazine, flurazepam, glutethimide, hydroxyamoxapine, imipramine, lorazepam, maprotiline, meperidine, metabolites, nortriptyline, oxazepam, pentobarbital, perphenazine, phenobarbital, phenytoin, propoxyphene, protriptyline, secobarbital, thioridazine, trazodone]... [Pg.86]

Noninterfering 7-aminoclonazepam, 7-aminoflunitrazepam, amitriptyline, amphetamine, diazepam, dothiepin, doxepin, ephedrine, mesoridazine, methadone, methamphetamine, nordiazepam, norpropo gq)hene, nortriptyline, oxazepam, propoxyphene, quinidine, quinine, sulfamethoxazole, sulforidazine, thioridazine, trimethoprim... [Pg.431]

Extracted acetazolamide, amitriptyline, chlordiazepoxide, chlorpromazine, desipramine, dextromethorphan, diphenhydramine, doxepin, encainide, fentanyl, flecainide, fluoxetine, flurazepam, haloperidol, hydroxyethylflurazepam, ibuprofen, imipramine, lidocaine, ma-protiline, methadone, methaqualone, mexiletine, norchlorimipramine, nordoxepin, norfluoxetine, nordiazepam, nortriptyline, norverapamil, pentazocine, promazine, propafenone, propoxyphene, propranolol, protriptyline, quinidine, temazepam, trazodone, tri-mipramine, verapamil... [Pg.461]

Extracted amitriptyline, benztropine, brompheniramine, chlorpheniramine, chlorproma-zine, clomipramine, ( roheptadine, desipramine, diphenhydramine, dothiepin, doxepin, haloperidol, imipramine, loxapine, maprotiline, meperidine, mesoridazine, methadone, metoclopramide, mianserin, moclobemide, nomifensine, nordoxepin, norfluoxetine, nor-propo q)hene, northiaden, nortriptyline, pentoharhital, pheniramine, promethazine, propoxyphene, propranolol, protriptyline, quinidine, quinine, sulforidazine, thioridazine, thiothixene, tranylcypromine, treizodone, trihe q)henidyl, trimipramine, triprolidine Noninterfering dextromethorphan, norphetidine, phenoxyhenzamine, prochlorperazine, trifluoperazine Interfering amoxapine... [Pg.628]

Noninterfering amitriptyline, amphetamine, atropine, benzoylecgonine, benztropine, caffeine, carbamazepine, carisoprodol, chlorpheniramine, chlorpromazine, chlorprothixene, cimetidine, cocaine, codeine, dextromethorphan, diazepam, diphenhydramine, diphenox-ilate, disopyramide, doxepin, dojylamine, emetine, erythromycin, flurazepam, gluteth-imide, hydrocortisone, hydromorphone, hydroxyzine, imipramine, lidocaine, loxapine, meperidine, meprobamate, methadone, methamphetamine, methapyrilene, methaqualone, methocarbamol, methylphenidate, nicotine, nordiazepam, nortriptyline, orphenadrine, papaverine, pentazocine, phenacetin, phencyclidine, phenmetrazine, phenolphthalein, phentermine, phenylpropanolamine, phenytoin, prazepam, procaineimide, procaine, propoxyphene, propranolol, protriptyline, pseudoephediine, pyrilamine, quinine, salicylam-ide, spironolactone, strychnine, terpin hydrate, thioridazine, thiothixene, triamterene, trifluoperazine, triflupromeizine, trihexyphenidyl, trimeprazine, trimethobenzamide, trimethoprim, tripeleimamine... [Pg.1347]

Noninterfering amitriptyline, amobarbital, ampicillin, butabarbital, butalbital, celbenine, chlordiazepoxide, chlorpromazine, clorazepate, desipramine, diazepam, doxepin, ethchlor-vynol, fluphenazine, hydroxyzine, ibuprofen, imipramine, isoniazid, lidocaine, mephobarbital, mesoridazine, methaqualone, methyluric acid, naprotyline, nordiazepam, nortriptyline, oxazepam, pentobarbital, perphenazine, phenelzine, phenmetrazine, phenobarbital, phenylbutazone, phenjdoin, prednisolone, prednisone, procainamide, prochlorperazine, promazine, promethazine, propoxyphene, protriptyline, pyrilamine, secobarbital, thioridazine, thiothixene, timolol, trazodone, triazolam, trifluoperazine... [Pg.1349]

The liver is the most important site of presystemic elimination because of high levels of drug-metabolizing enzymes, its ability to rapidly metabolize different types of drugs, and its unique anatomical location. The following are selected examples of drugs that are subject to considerable hepatic first-pass metabolism the 3-blockers propranolol and metoprolol the analgesics propoxyphene, meperidine, and pentazocine the antidepressants imipramine and nortriptyline and the antiarrhythmic lidocaine. [Pg.396]

The amitriptyline concentration/dose ratio in 12 patients given amitriptyline and dextropropoxyphene was raised by about 20% (suggesting raised amitriptyline levels), when compared with other patients taking amitriptyline alone. Similarly, the plasma levels of the amitriptyline metabolite nortriptyline was raised by about 30% in 14 patients given dextro-propoxyphene and in another study nortriptyline plasma levels were raised by 16% by dextropropoxyphene. ... [Pg.187]

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