Tris- -nitromethane

TMNTA 1,1,1 -Tris(hydroxymethyl)nitromethane tris(azidoacetate) ester... 

B-3 Industrial Bacteriostat Bioban CWT S.S.T. Sump Saver Tablets Tris (hydroxymethyl) nitromethane Tris Nitro ... 

Nitro-derivatives. Examples of condensation products from CH-acid compounds with formaldehyde are the reaction products tris-(hydroxymethyl)-nitromethane (tris-nitro) (II, 3.2.1.) and N-nitrobutyl-morpholine (II, 3.2.3.). 

Nitromethane is the most reactive nitroalkane that favors strong reaction to the tris adduct (see Nitroalcohols). 

Tris(hydroxymethyl)nitromethane," Reregistration Eligibility Decision, U.S. EPA, Washington, D.C., 1993. 

Tris-(hydroxymethyl)nitromethane [2-(hydroxymethyl)-2-nitro-l,3-propanediol] [126-11-4] M 151.1, m 174-175°(dec, tech grade), 214°(pure). Crystd from CHCl3/ethyl acetate or ethyl acetate/ benzene. It is an acid and a O.IM sol in H2O has pH 4.5. IRRITANT. 

Nitromethane is reacted with formaldehyde to give tris(hydroxymethyl)nitromethane in an initial step. This Intermediate may be reduced by catalytic hydrogenation (U.S. Patent 2,174,242) or by electrolytic reduction (U.S. Patent 2,485,982),... 

A kinetic isotope effect, kH/kD = 1.4, has been observed in the bromination of 3-bromo-l,2,4,5-tetramethylbenzene and its 6-deuterated isomer by bromine in nitromethane at 30 °C, and this has been attributed to steric hindrance to the electrophile causing kLx to become significant relative to k 2 (see p. 8)268. A more extensive subsequent investigation304 of the isotope effects obtained for reaction in acetic acid and in nitromethane (in parentheses) revealed the following values mesitylene, 1.1 pentamethylbenzene 1.2 3-methoxy-1,2,4,5-tetramethyl-benzene 1.5 5-t-butyl-1,2,3-trimethylbenzene 1.6 (2.7) 3-bromo-1,2,4,5-tetra-methylbenzene 1.4 and for 1,3,5-tri-f-butylbenzene in acetic acid-dioxan, with silver ion catalyst, kH/kD = 3.6. All of these isotope effects are obtained with hindered compounds, and the larger the steric hindrance, the greater the isotope... 

The ligand tris[2-(l-methylbenzimidazol-2-yl)ethyl] nitromethane (25) has been used in the formation of zinc complexes as models of the active site of carbonic anhydrase, and the formed complexes reveal affinity for the sulfonamide-containing enzyme inhibitor acetazolamide.248... 

Interaction of nitromethane and formaldehyde in presence of alkali gives not only 2-nitroethanol, but also di- and tri-condensation products. After removal of the 2-nitroethanol by vacuum distillation, the residue must be cooled before admitting air into the system to prevent a flash explosion or violent fume-off. 

Tris(hydroxymethyl)nitromethane See other non-metals, reducants See Tris(hydroxymethyl)nitromethane Hydrogen etc. 

The first addition of nitroalkanes to glycals was recently described. It involved a radical mediated addition of nitromethane to tri-O-benzyl-D-glucal (48) in the presence of CAN and KOH and methanol as solvent, to give the diastereomeric mixture 49 + 50 (Scheme 18).42... 

Biocides that function as formaldehyde-releasers comprise about 60 % of total sales of antimicrobials (29). Thus, such antimicrobials are expected to be common additions to metalworking fluids. Examples of formaldehyde-releasing antimicrobials are tris(hydroxy methyl) nitromethane, trivially called tris nitro, 4,4 -(2-ethyl-2-... 

The lead salts of nitromethane, mono-, di- or tri-nitrophenols bum at faster rates (up to 640-fold) than the parent compounds. Lead salts of trinitromethane, trini-trobutyric acid or dinitro-benzoic or -p-toluic acids bum at slightly faster rates (up to 10-fold) than the parent compounds. 

Both tris(2,2,2-trinitroethyl)orthoformate and tetrakis(2,2,2-trinitroethyl)-orthocar-bonate form powerfully explosive solutions in nitromethane. The oxygen balance of the esters are +154 and +182%, respectively. The compounds are Tetrakis(2,2,2-trinitroethyl)orthocarbonate, 3132 Tris(2,2,2-trinitroethyl) orthoformate, 2786 See OXYGEN BALANCE, POLYNITROALKYL COMPOUNDS... 

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