New methylene blue

The available evidence supports the demethylation scheme and the identity of the initial red product as that of the basic tautomer of trimethylthionine (Azure B), as shown in eqs. 33 and 34. Addition of acid or other weak proton donor protonates the red dye to give the blue form. We have reexamined the reaction of MB or New methylene blue (NMB) in dry acetonitrile with tri-ethylamine (TEA). We have also found that a comparable reaction of NMB occurs with trimethylbenzylstannane (TMBS). Figure 8 shows changes in the visible spectrum of NMB which occur in addition of TEA. Table 12 lists quantitative data. The spectra... 

Methylene blue, new methylene blue, thionine blue, Capri blue, cresyl blue, brilliant cresyl blue, Nile blue, Basle blue, Mel-dola s blue, fast navy blue, new blue, metamine blue, naphthol u, blue, metaphenylene blue, paraphenylene blue, mdamine blue, indazine, neutral blue, muscanne, diphene blue, rhoduline blue, rhoduline sky blue frl ... 

Fig. 5. Filtration of the white blood cells from diluted human whole blood using a comb-type filter chip. The white blood cells were stained with New Methylene Blue dye. The image was taken by reversing the applied pressure slightly to allow the trapped white cells be released from the front surface of the filters (arrow) and be seen clearly [3]...

Fig. 6. Filtration of the white blood cells from New Methylene Blue dye stained undiluted human whole blood using a weir-type filter chip (flows direction is indicated by the arrow). The image was taken during the filtration process. The purple-blue particles seen in the middle of the chip were the stained white cells trapped on the surface of the weir filter...

In a notable paper, Lee et al. [41] examined the dimerization and inclusion complexation equilibria of six phenothiazine dyes, including thionine (TH), azure A (AZA), methylene blue (MB), toluidine blue (TB), new methylene blue (NMB) and 1,9-dimethylmethylene blue (DMMB) (Fig. 2), with CDs (a-, (>-, and y-CDs) in aqueous medium. These phenothiazine dyes presented their structural differences in the position and number of methyl substituents located on the same phenothiazine skeleton. By means of the UV-visible absorption and fluorescence spectra, the authors studied the factors which were responsible for the dimerization of phenothiazine dyes with CDs, in terms of a multiple equilibrium system (Scheme 1). In addition, the authors also determined the JCd values and the corresponding association constants of the monomers (M) and dimers (D) with the CDs [41]. 

The antibacterial activity of two novel compounds, phenothiazinium new methylene blue N and phenoxazinium brilliant cresyl blue, was investigated [124]. It was found that the two compounds exhibited their bactericidal activity at lower concentrations when compared to the well-established phenothiaziniums, such as methylene blue and toluidine blue O, as well as a recently synthesized blood photovirucidal agent of 1,9-dimethyl-methylene blue. The photoactivity of these compounds was undiminished in the presence of red blood cells [ 124],... 

Methylene Green New Methylene Blue H New Methylene Blue A... 

Liu H, Ying T, Sun K et al. A reagentless biosensor highly sensitive to hydrogen peroxide based on new methylene blue N dispersed in Nafion gel as the electron shuttle. J Electroanal Chem 1996 417 59-64. 

Methylthioninium chloride, in M-00175 Muscarinef Chloride, in M-00350 Neutral blue Chloride, in N-00064 New methylene blue NCG Chloride, in... 

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