Neurological and Psychiatric Symptoms of Aluminum Poisoning

TABLE 6-2. Neurologica attributed to land psychiatric signs, symptoms, and syndromes aluminum exposure 

Neurological Dementia, dyspraxia, myoclonus, seizures, grimacing, speech arrest, dysarthria, dysphagia, abnormal electroencephalogram findings, asterixis, tremor 

Psychiatric Mood Mood lability, depression, anxiety Behavior Agitation, violence, personality change, bizarre behavior, suicidal, homicidal Cognitive Memory loss, poor concentration, confusion Perceptual Hallucinations, paranoia Other Insomnia 

Other Pulmonary fibrosis, bronchopneumonia, anemia, osteodystrophy, amyotrophic lateral sclerosis and parkinsonism-dementia of Guam, macrophagic myofasciitis 

Macrophagic myofasciitis (MMF) is a recently identified demye-linating central nervous system disorder attributed to intramuscular injections of aluminum-containing vaccines. Symptoms of 1 of 92 cases included cognitive and behavioral changes (Authier et al. 2001). Another new disorder attributed to an inherited abnormality of aluminum metabolism causes progressive and fatal central nervous system calcification (Meshitsuka et al. 2001). 

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