Natural hyaluronic acid composites

The temperature of the solution has both the effect of increasing its evaporation rate and reducing the viscosity of the polymer solution, thus enabling the polymer solution which was spinnable under room temperature to be electrospun easily. For example, the hyaluronic acid is a natural polyelectrolyte that is hard to be electrospun under room temperature [27]. Li et al. [83] used the high electrospinning temperature that was higher than the gel temperature of hyaluronic acid (40 °C) and thus successfully fabricated hyaluronic acid composite nanofibers with uniform morphology. Similar method was also suitable for the fabrication of other natural... 

We were successful earlier in achieving anioiuc/cationic complexes with glycosaminoglycans, e.g., hyaluronic acid/cationic polysaccharide compositions [44], now used in personal care applications. Those compositions are substantive, stable and user-friendly. Unfortunately, despite the highly anionic nature of hyaluronic acid (and other glycosaminoglycans), these materials do not block viral infections [39]. Furthermore, as shown by the in vivo rabbit irritation studies, such compositions displayed minimal irritation [13]. 

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