Narcotic pollutants

Urrestarazu Ramos, E., Vaes, W, Verhaar, H.J. and Hermens, J.L. (1998). Quantitative Structure-Activity Relationships for the Aquatic Toxicity of Polar and Nonpolar Narcotic Pollutants. J.Chem.lnf.Comput.ScL, 38,845-852. 

Ivanciuc, O. (2003a) Aquatic toxicity prediction for polar and nonpolar narcotic pollutants with support vector machines. Internet Electron. ]. Mol. Des., 2, 195-208. 

Using a descriptor selection procedure, we found that only three descriptors ( homo lumo nd Q ) are essential for the SVM model. To exemplify the shape of the classification hyperplane for polar and nonpolar narcotic pollutants, we selected 20 compounds (Table 7) as a test set (nonpolar compounds, class +1 polar compounds, class —1). 

Detection and quantification of trace chemicals are a major thrust of analytical chemistry. In recent years, much effort has been put into developing detection systems for priority pollutants. Less mature are the detections of substances of interest to law enforcement and security personnel narcotics, chemical agents, and explosives. This volume will discuss the detection of the latter, emphasizing explosive detection both because of its public importance and because it has undergone remarkable developments in the last decade. 

One of the more important areas of use of ultraviolet instruments is the identification and determination of biologically active substances. Many components in body fluids can be determined either directly or through colorimetric methods. Drugs and narcotics can be measured both in the body as well as in formulations. Vitamin assay is another related activity. Nearly all metals and nonmetals can be determined through their ultraviolet absorption or by colorimetric methods. In recent years, ultraviolet instruments have been used extensively for the determination of air and water pollutants, such as aldehydes, phenolics, and ozone ... 

Van Leeuwen, C.J., Van Der Zandt, P.T.J., Aldenberg, T., Verhaar, H.J.M., Hermens, J.L.M. (1992) Application of QSARs, extrapolation and equilibrium partitioning in aquatic effects assessment. I. Narcotic industrial pollutants. Environ. Toxicol. Chem. 11,267-282. 

A common theme throughout this volume involves the adsorption and interfacial, especially biointerfacial, behaviour of all of the above mentioned nanomaterials. For environmental and human protection, the adsorption of heavy metal ions, toxins, pollutants, drugs, chemical warfare agents, narcotics, etc. is often desirable. A healthy mix of experimental and theoretical approaches to address these problems is described in various contributions. In other cases the application of materials, particularly for biomedical applications, requires a surface rendered inactive to adsorption for long term biocompatibility. Adsorption, surface chemistry, and particle size also plays an important role in the toxicological behaviour of nanoparticles, a cause for concern in the application of nanomaterials. Each one of these issues is addressed in one or more contributions in this volume. 

Pharamaceuticals Biochemicals Food products Industrial chemicals Pollutants Forensic chemistry Clinical medicine Antibiotics, sedatives, steroids, analgesics Amino acids, proteins, carbohydrates, lipids Artificial sweeteners, antioxidants, aflatoxins, additives Condensed aromatics, surfactants, propellants, dyes Pesticides, herbicides, phenols, polychlorinated biphenyls (PCBs) Dmgs. poisons, blood alcohol, narcotics Bile acids, drug metabolites, urine extracts, estrogens... 

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