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Nanoparticle delivery systems, microparticle

A large variety of drug delivery systems are described in the literature, such as liposomes (Torchilin, 2006), micro and nanoparticles (Kumar, 2000), polymeric micelles (Torchilin, 2006), nanocrystals (Muller et al., 2011), among others. Microparticles are usually classified as microcapsules or microspheres (Figure 8). Microspheres are matrix spherical microparticles where the drug may be located on the surface or dissolved into the matrix. Microcapsules are characterized as spherical particles more than Ipm containing a core substance (aqueous or lipid), normally lipid, and are used to deliver poor soluble molecules... [Pg.70]

Wendorf J, Chesko J, Kazzaz J et al (2008) A comparison of anionic nanoparticles and microparticles as vaccine delivery systems. Hum Vaccin 4 44-49... [Pg.64]

Polymeric Nanoparticles or Microparticles-Based Gene Delivery System... [Pg.356]

Microparticles and nanoparticles present some advantageous features, namely mucoadhesive properties. They have demonstrated some potential in vaginal drug delivery, particularly in the formulation of delivery systems for vaccines or peptides and proteins [160, 161], Nonetheless, these particles have to be incorporated in adequate carrier systems in order to be delivered. This task has been shown to be complex, it being hard to achieve controlled-release and steady-release profiles. [Pg.834]

Singh M, Chakrapani A, O Hagan D (2007) Nanoparticles and microparticles as vaccine-delivery systems. Expert Rev Vaccines 6 797-808... [Pg.174]

Figure 1 Formulation of controlled drug delivery systems using the supercritical fluid-derived RESS process (A) films, (B) microparticles/nanoparticles/ liposomes, (C) coated products including microcapsules, and (D) microporous foams. Figure 1 Formulation of controlled drug delivery systems using the supercritical fluid-derived RESS process (A) films, (B) microparticles/nanoparticles/ liposomes, (C) coated products including microcapsules, and (D) microporous foams.
Nanoparticles and/or capsules are colloidal drug delivery systems whose size ranges from 1 to 1000 nm. Similar to microparticles, nanoparticles also offer... [Pg.383]

Z. Cui and R. J. Mumper, Microparticles and nanoparticles as delivery systems for DNA vaccines, Critical Rev. Ther. Drug Carrier Syst. [Pg.1504]

Figure 9.24 Particles for drug delivery. Particulate delivery systems include (a) microcapsules, (b) microparticles, and (c) surface-modified nanoparticles. In the nanoparticles, the drug is entrapped in the solid pol)mier core. Figure 9.24 Particles for drug delivery. Particulate delivery systems include (a) microcapsules, (b) microparticles, and (c) surface-modified nanoparticles. In the nanoparticles, the drug is entrapped in the solid pol)mier core.
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