Nano-liquid chromatography

Alexander IV, J.N., Poli J.B., and Markides K.E., Evaluation of automated isocratic and gradient nano-liquid chromatography and capillary electrochromatography, Anal. Chem. 71, 2398, 1999. 

Nagele, E., Vollmer, M., Horth, P. (2003). Two-dimensional nano-liquid chromatography— mass spectrometry system for applications in proteomics. J. Chromatogr. A1009,197-205. 

Tyan, Y.C., Wu, H.Y., Lai, W.W., Su, W.C., Liao, PC. (2005b). Proteomic profiling of human pleural effusion using two-dimensional nano liquid chromatography tandem mass spectrometry. J. Proteome Res. 4, 1274-1286. 

Calvo, E., Flores-Romero, P., Lopez, J. A., and Navas, A., Identification of proteins expressing differences among isolates of Meloidogyne spp. (Nematoda Meloidogynidae) by nano-liquid chromatography coupled to ion-trap mass spectrometry. Journal of Proteome Research 4(3), 1017-1021, 2005. 

Ficarro, S. B., Salomon, A. R., BriU, L. M., Mason, D. E., Stettler-GiU, M., Brock, A., and Peters, E. C., Automated immobilized metal affinity chromatography/nano-liquid chromatography/electrospray ionization mass spectrometry platform for profiling protein phosphorylation sites, Rapid Communications in Mass Spectrometry 19(1), 57-71, 2005. 

Mitulovic, G., Stingl, C., Smoluch, M., Swart, R., Chervet, J. P., Steinmacher, I., Gerner, C., and Mechtler, K., Automated, on-line two-dimensional nano liquid chromatography tandem mass spectrometry for rapid analysis of complex protein digests, Proteomics 4(9), 2545-2557, 2004. 

Fanali, S., Aturkil, Z., D Orazio, G., Raggi, M. A., Quaglia, M. G., Sabbioni, C., and Rocco, A., Use of nano-liquid chromatography for the analysis of glycyrrhizin and glycyrrhetic acid in licorice roots and candies. Journal of Separation Science 28(9-10), 982-986, 2005. 

Reverse-phase columns with a gradient elution in combination with UV-Vis spectrophotometers using photodiode-array (PDA) (Fig. 1.6) and spectrofiuorimeters are common devices employed in this technique. In a lesser extent, MS, tandem mass spectrometry (MS-MS), and nano liquid chromatography-electrospray ionization-quadrupole time-of-flight tandem mass spectrometry (nanoLC-nanoESI-Q-qTOF-MS-MS) has been used as detection system. This instrumentation has been mainly used in the analysis of dyes and proteinaceous media, and in some extent, in the analysis of drying oils and terpenoid varnishes [47,48],... 

Lanckmans, K., Sane, S., Smolders, I., and Michotte, Y. (2007). Use of a structural analogue versus a stable isotope labeled internal standard for the quantification of angiotensin IV in rat brain dialysates using nano-liquid chromatography/tandem mass spectrometry. Rapid Commun. Mass Spectrom. 21 1187-1195. 

Q. He, Integrated nano liquid chromatography system on a chip, Ph.D. thesis, California Institute of Technology, Pasadena, CA, June 21 (2005). 

Glycomics Glycopeptides Glycoproteomics Mass spectrometry Nano liquid chromatography iV-glycans 0-glycans Profiling Structural analysis Tandem mass spectrometry... 

Canas, I.R., Hamilton, B., Amandi, M.F., Furey, A., and James, K.J., Nano liquid chromatography with hybrid quadrupole time-of-flight mass spectrometry for determination of yessotoxin in marine plankton. J. Chromatogr. A, 1056, 253, 2004. 

Table 2.2. Differences between preparative, analytical, micro and nano liquid chromatography.

Fanali, S. Camera, E. Chankvetadze, B. D Orazio, G. Quaglia, M.G. Separation of tocopherols by nano-liquid chromatography. J. Pharm. Biomed. 2004, 35, 331-337. 

L.O. Healy, J.P. Murrihy, A. Tan, D. Cocker, M. McEnery and J.D. Glennon, Enantiomeric separation of R,S-naproxen by conventional and nano-liquid chromatography with methyl-beta-cyclodextrin as a mobile phase additive, J. Chromatogr. A, 2001, 924, 459-464. 

Frohlieh T, Arnold GJ. A neweomer s guide to nano-liquid-chromatography of peptides. In Reinders J, Siekmann A, editors. Proteomies, methods in molecular biology. Vol. 564. Springer, Heidelberg 2009. p. 123 1. doi 10.1007/978-l-60761-157-8 7. 

Karu, K., Turton, J., Wang, Y. and Griffiths, W.J. (2011) Nano-liquid chromatography-tandem mass spectrometry analysis of oxysterols in brain Monitoring of cholesterol autoxidation. Chem. Phys. Lipids 164,411-424. 

Fanali S, Orazio GD, Lomsadze K, Samakashvili BS, Chankvetadze B. Enantioseparations with amylose(5-chloro-2-methlphenylcarbamate) in nano liquid chromatography and capillary electrochromatography. J Chromatogr A 2010 1217 1166-74. 

Although quite a deal of work has been done on the miniaturization of the components and devices integrated in chromatographic and electrophoretic equipment, miniaturization of the whole apparatus is not yet a reality. In fact, miniaturization is only achieved when chromatographic or electrophoretic separations are carried out in chips where all the principles of micro- and nanofluidics are involved, these systems being connected to the lab-on-a-chip approaches. The common characteristics associated with nano-liquid chromatography (nano-LC) techniques include column internal diameters between 10... 

Aqay, P., J. Peters, A. Gerssen, W. Haasnoot, and M. W. F. Nielen. 2011. Immunomagnetic microbeads for screening with flow cytometry and identification with nano-liquid chromatography mass spectrometry of ochratoxins in wheat and cereal. Anal. Bioanal. Chem. 400 3085-3096. 

Karlsson, N. G. Wilson, N. L. Wieth, H.-J. Dawes, P. JosHi, H. Packer, N. H. Negative ion graphitised carbon nano-liquid chromatography/mass spectrometry increases sensitivity for glycoprotein oligosaccharide analysis. Rapid Commun. Mass Spectrom. 2004, 18, 2282-2292. 

Rosales-Conrado N, Leon-Gonzalez ME, Rocco A, Fanali S. Enantiomeric separation of ofloxacin by nano-liquid chromatography using a sulfated-p-cyclodextrin as a chiral selector in the mobile phase. Current Anal Chem. 2010 6 209-216. 

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