NaNH2 Sodium amide

Acid NH4C1, ammonium chloride Base NaNH2, sodium amide... 

NaNH2 Sodium amide H2SO4 Sulfuric acid. S ... 

Predict the major product when each reagent reacts with ethylene oxide, (a) NaOCH2CH3 (sodium ethoxide) (b) NaNH2 (sodium amide)... 

NaNH2 sodium amide 7782-92-5 20.00 1.3900 1 3085 Nd2H16O20S3 neodymium sulfate octahydrate 13477-91-3 25.00 2.8500 1... 

NaGe(C6H6)i Sodium (triphenyl-germyl)-, 6 72, 74 NaH Sodium hydride, 6 10, 13 NaNH2 Sodium amide, 1 74 2 80, 128... 

Among compounds named like binary compounds are NaNH2, sodium amide KNs, potassium azide CaNCN, calcium cyanamide. These electronegative groups and others (not including radicals of oxygen acids and thio acids except the cyanates) are named in the best accepted manner ... 

Water can also be a Brpnsted acid donating a proton to a base Sodium amide (NaNH2) for example is a source of the strongly basic amide ion which reacts with water to give ammonia... 

Solutions of sodium acetylide (HC=CNa) may be prepared by adding sodium amide (NaNH2) to acetylene m liquid ammonia as the solvent Terminal alkynes react similarly to give species of the type RC=CNa... 

Nucleophilic aromatic substitution can also occur by an elimination-addition mechanism This pathway is followed when the nucleophile is an exceptionally strong base such as amide ion m the form of sodium amide (NaNH2) or potassium amide (KNH2) Benzyne and related arynes are intermediates m nucleophilic aromatic substitutions that pro ceed by the elimination-addition mechanism... 

Potassium dissolves in Hquid ammonia, but the conversion of a small amount of the metallic potassium to the metallic amide takes several days. By applying the same technique using sodium metal, sodium amide [7782-92-5] NaNH2, a white soHd, can be formed. 

Phosphoms trichloride and pentachloride form sodium chloride and sodium phosphide, respectively, in the presence of sodium. Phosphoms oxychloride, POCl, when heated with sodium, explodes. Carbon disulfide reacts violendy, forming sodium sulfide. Sodium amide (sodamide), NaNH2, is formed by the reaction of ammonia gas with Hquid sodium. SoHd sodium reacts only superficially with Hquid sulfur dioxide but molten sodium and gaseous... 

The amide ion (NH2) of sodium amide (NaNH2) is a very powerful base ... 

It has been found that this reaction is catalyzed by sodium amide, NaNH2. The function of the catalyst... 

Caubere et al. [63, 64] treated 32a with sodium amide-sodium tert-butoxide (NaNH2-NaOtBu) in tetrahydrofuran (THF) in the presence of secondary amines and obtained enamines. Analogously, the corresponding thioenol ethers were formed from 32a and sodium amide-sodium thiolate in the presence or absence of NaOtBu. It was shown, however, that cyclohexyne rather than 6 is the decisive intermediate en route to the enamines as well as the thioenol ethers [63b, 64], As already mentioned above, the enol ether 41 arises inter alia from 32b and KOtBu in DMSO. The best yield (47%) was obtained in refluxing THF (Scheme 6.11) [60],... 

The NaOH in the reaction can be replaced with NaNH2, because the amide ion, NH2, is similar to the hydroxide ion in that both are strong bases and good nucleophiles (the amide ion is a much stronger base). The use of sodium amide yields aniline as the product. 

Preparation of primary amines Alkyl halide reacts with sodium amide (NaNH2) to give 1° amine via Sn2 reaction. The reaction mechanism for the formation of 1° amine is similar to the formation of nitrile. 

The synthesis of sodium amide, NaNH2 (or sodamide ), by passing ammonia over heated sodium metal, was first reported almost two centuries ago. A number of studies have since been made of its properties, but no crystal structure has been reported. Sodamide is used as a strong base in organic chemistry (often in liquid ammonia solution). In contrast, sodium bis(trimethylsilyl)amide NaN(SiMe3)2 (or sodium hex-amethyldisilazide , NaHMDS), whose crystal structure is discussed later, is widely used for deprotonation reactions or base catalysed reactions due to its solubility in a wide range of non-polar solvents. An overview of some of the types of chemical reactions in which NaHMDS is used is presented in Scheme 2.3. 

Sodium Amide or Sodamide, NaNH2. Wh crysts, mp 206.4° dissolves in liq NH3 and is vigorously hydrolyzed by HjO. Was first prepd ca 1810 by Gay-Lussac and Thenard by the action of NH3 gas on molten metallic Na heated to 300°. Can also be prepd by dissolving metallic Na in liq NH3 and then placing in the soln a a spiral of. Fe wire, which catalytically accelerates the otherwise very slow reaction Na + NH NaNH2 + H Mixts of sodamide with nitrates and chlorates expl when triturated (Ref 1, p 255)... 

Explain why sodium amide (NaNH2) and phenyl lithium (C6H5Li) are leveled to the same base strength in aqueous solution. Write the chemical reactions that occur when these are added to water. 

---