Nalorphine hydrochloride

Thiamine Mononitrate Thiamine Hydrochloride 347.8 Nalorphine Hydrochloride... 

In 1915, it was shown that N-allylnorcodeine abolished both heroine- and morphine-indueed respiratory depression. Almost 25 years later (1940), it was observed that N-allylnormorphine (eom-monly known as nalorphine) possessed more marked and signifieant morphine antagonizing aetions. Thirteen years later (1953), it was demonstrated that nalorphine had the ability to arrest severe abstinence syndromes in postaddicts who were earlier treated briefly with either morphine, methadone or heroine. Examples of narcotic antagonists include nalorphine hydrochloride naloxone hydrochloride propiram fnmarate and pentazocine. 

CBrN 506-68-3) see Anagrelide hydrochloride Desloratadine Epinastine hydrochloride Fluoxetine Nalorphine Naloxone Pergolide cyanogen chloride... 

Alphaprodine hydrochloride is administered by subcutaneous injection in doses of 40 to 60 mg depending upon the weight of the patient. Analgesia occurs within 5 min and lasts about 2 h. Nalorphine is an effective antidote to overdosage. 

Naloxone (Narcan) and naltrexone hydrochloride (Trexan) reverse the respiratory depressant action of narcotics related to morphine, meperidine, and methadone. They differ from other narcotic analgesics in several respects. Naloxone does not cause respiratory depression, pupillary constriction, sedation, or analgesia. However, it does antagonize the actions of pentazocine. Naloxone neither antagonizes the respiratory depressant effects of barbiturates and other hypnotics nor aggravates their depressant effects on respiration. Similar to nalorphine, naloxone precipitates an abstinence syndrome when administered to patients addicted to opiate-like drugs. 

Nalorphine Hydrobromide 406.4 Codeine Phosphate Prazosin Hydrochloride... 

Quinidine Sulphate Amidephrine Mesylate Pipoxolan Hydrochloride Polythiazide Amodiaquine Guanoclor Sulphate Methyl Benzoquate Nalorphine Oxyclozanide Bamipine Hydrochloride Albendazole Chlormadinone Acetate Sulphamethizole Buprenorphine Fludrocortisone Acetate Hydroxyephedrine Hydrochloride Lormetazepam Sulphamethoxydiazine Bialamicol Hydrochloride Bunamidine Hydrochloride Hordenine Sulphate (dried) Mesterolone Carbidopa... 

Perly, Pappalardo and Grassi [41, 43] have analysed the 600 MHz H-NMR spectra of morphine, nalorphine and oxymorphone hydrochlorides and obtained evidence of molecular conformation from V coupling magnitudes. 

Figure 5.9. Newman projections for conformations about C-C bonds for hydrochloride salts of morphine (72 °C), nalorphine (57 °C) (AMM) and oxymorphone (23 °C) (A-E). Both conformations A and B are compatible with values. Calculation of the rotation angle for which in A gives an...

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