N-Linked Glycans from the Gram-Negative Bacterium jejuni

2 N-Linked Glycans from the Gram-Negative Bacterium C. jejuni 

SCHEME 14.21 Synthesis of the O-linked oligosaccharide of BclA by Seeberger and coworkers. AIBN, azobisisobutyronitrile TCA, trichloroacetyl. 

SCHEME 14.22 Synthesis of N-linked oligosaccharide and lipid-linked oligosaccharide from Campylobacter jejuni by Ito and coworkers. DAST, N, iV-die thy lamino sulfur trifluoride. 

There is no doubt about the successful chemical syntheses of the glycan cell-wall components, and these approaches could be further applied to synthetic and biological studies on this area. After the discovery of antibiotics targeting the cell-wall biosynthesis, it became possible to control previously serious pathogenic bacteria, although 

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