Myxedema

Myrrh [8016-37-3] Myrrh [9000-45-7] Mysid shrimp Mystore de Rochas Myxedema... 

Myxedema and goiter are the main conditions for which thyroid preparations are indicated. The treatment of cretinism is difficult because it is recognized only at or after birth. Even if this disease could be diagnosed m utero, thyroid hormones do not readily cross the placental barrier. In addition, the fetus, as does a premature infant, rapidly deactivates the thyroid hormones. The halogen-free analogue DlMlT [26384-44-7] (3), which is resistant to fetal deiodinases, may prove useful for fetal hypothyroidism (cretinism). 

Endocrine diseases autoimmune thyreoiditis, primary myxedema, Addison s disease, type 1 diabetes mellitus (IDDM)... 

Myxedema is a severe hypothyroidism manifested by lethargy, apathy, memory impairment, emotional changes, slow speech, deep coarse voice, thick dry skin, cold intolerance, slow pulse, constipation, weight gain, and absence of menses. 

Thomas AE, Gisburn MA (1961) Exogenous ochronosis and myxedema from resorcinol. Br J Dermatol 73 378-381... 

Hypothyroidism can affect virtually any tissue or organ in the body. However, the most common symptoms, such as fatigue, lethargy, sleepiness, cold intolerance, and dry skin, are nonspecific and are seen with many other disorders. The classic overt signs, such as myxedema and delayed deep tendon reflexes, are seen uncommonly now because more patients are... 

Myxedema coma is seen in advanced hypothyroidism. These patients develop CNS depression, respiratory depression, cardiovascular instability, and fluid and electrolyte disturbances. Myxedema coma often is triggered by an underlying acute medical condition such as infection, stroke, trauma, or administration of CNS depressant drugs. 

Myxedema Advanced hypothyroidism characterized by a relatively firm edema of subcutaneous tissue, subnormal body temperature, dryness and loss of hair, hoarseness, and muscle weakness. 

Thyroid Disease. Hypothyroidism (myxedema) [169] and hyperthyroidism [170] alter small bowel motility. Although today these diseases are usually recognized before such symptoms develop, thyroid function must be examined in unexplained intestinal pseudoobstruction. 

Abbasi AA, Douglass RC, Bissell GW, Chen Y Myxedema ileus A form of intestinal pseudoobstruction. JAMA 1975 234 181-183. 

The treatment of myxedema coma can include which of the following agents ... 

The following factors have been suggested as alternatives to consider when presented with a potential case of exposure to carbon monoxide diabetic ketoacidosis, hypothyroidism and myxedema coma, labyrinthitis, and lactic acidosis toxic exposures resulting in methemoglobinemia ingestion of alcohols or narcotics and diseases that cause gastroenteritis, encephalitis, meningitis, and acute respiratory distress syndrome. 

Myxedema coma is a rare consequence of decompensated hypothyroidism manifested by hypothermia, advanced stages of hypothyroid symptoms, and altered sensorium ranging from delirium to coma. Untreated disease is associated with a high mortality rate. 

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