Mycoplasma sp.

Uses Broad-spectrum antibiotic Action Bacteriostatic protein synth Spectrum Gram(+) Staphylococcus sp, Streptococcus sp Gram(-) H. pylori Atypicals Chlamydia sp, Rickettsia sp, Mycoplasma sp Dose Adults. 250-500 mg PO bid—qid Peds > 8 y. 25-50 mg/kg/24 h PO q6-12h i w/ renal/hepatic impair, w/o food preferred Caution [D, +] Contra PRG, antacids, w/ dairy products, children <8 y Disp Caps 100, 250, 500 mg tabs 250, 500 mg PO susp 250 mg/5 mL SE Photosens, GI upset, renal failure, pseudotumor cerebri, hepatic impair Interactions T Effects OF anticoagulants, cligoxin effects W/ antacids, cimeticline, laxatives, penicillin, Fe supl, dairy products effects OF OCPs EMS T Effects of anticoagulants monitor for signs of electrolyte disturbances and hypovolemia d/t D ... 

SJS/TEN are clearly different from erythema exsudativum multiforme, which is mainly caused by viral infections (Mockenhaupt 2007), is often recurrent, and affects younger persons (mean age 24 years). In about 6% of SJS/TEN cases, no drug treatment was reported the week before SJS/TEN started, and an infectious origin (Mycoplasma sp., Klebsiella sp.) is suspected. SJS/TEN can also be due to a graft versus host disease. 

Fig. 6. Distribution of the most common folds in selected bacterial, archaeal, and eukaryotic proteomes. The vertical axis shows the fraction of all predicted folds in the respective proteome. Fold name abbreviations FAD/NAD, FAD/NAD(P)-binding Rossman-like domains TIM, TIM-barrel domains SAM-MTR, S-adenosylmethionine-dependent methyltransferases PK, serine-threonine protein kinases PP-Loop, ATP pyrophosphatases. mge, Mycoplasma genitalium rpr, Rickettsiaprowazekii hh x, Borrelia burgdorferi ctr, Chlamydia trachomatis hpy, Helicobacter pylori tma, Thermotoga maritima ssp, Synechocystis sp. mtu, Mycobacterium tuberculosis eco, Escherichia coli mja, Methanococcus jannaschii pho, Pyrococcus horikoshii see, Saccharomyces cerevisiae, cel, Caenorhabditis elegans.

A combination of trimethoprim-sulfamethoxazole is effective treatment for a wide variety of infections including P jiroveci pneumonia, shigellosis, systemic salmonella infections, urinary tract infections, prostatitis, and some nontuberculous mycobacterial infections. It is active against most Staphylococcus aureus strains, both methicillin-susceptible and methicillin-resistant, and against respiratory tract pathogens such as the pneumococcus, Haemophilus sp, Moraxella catarrhalis, and Klebsiella pneumoniae (but not Mycoplasma pneumoniae). However, the increasing prevalence of strains of E coli (up to 30% or more) and pneumococci that are resistant to trimethoprim-sulfamethoxazole must be considered before using this combination for empirical therapy of upper urinary tract infections or pneumonia. 

Staal SP, Rowe WP. Differential effect of phenylethyl alcohol on mycoplasmas and enveloped viruses. / Viro/1974 14 1620-1622. 

Soil organisms degrading chlorophenoxyacetic acids are mainly bacteria and a few Actinomyceta species. Among such bacterial species are Achromobacter, Arthrobacter, Corynebacterium, Flavobacterium, Mycoplasma and Rhizobium sp. 

Morganella morganii Mycoplasma hominis Neisseria sp. Proteus sp. Providencia sp. Pseudomonas sp. Salmonella sp. Serratia sp. Shigella sp. Ureaplasma urealyti-cum Vibrio sp. Streptococcus pyogenes ... 

Haberer K, Haberer AI, Cadden SP, Maniloff J. Isolation and characterization of mycoplasma vims L3 temperature-sensitive mutants. Microbios. 1990 64 111-25. 

Lai WC, Bennett M, Pakes SP, Kumar V, Steutermann D, Owusu 1, et al. Resistance to Mycoplasma pulmonis mediated by activated natural killer cells. J Infect Dis 1990 161 1269 1275. 

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