Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Musca domestica, cytochrome

One of the sex pheromone components of the housefly, Musca domestica, is Z9-21 H that is found on the cuticular surface of the fly. This compound is formed by the elongation of Z9-18 CoA using malonyl-CoA and NADPH to Z15-24 CoA which is decarboxylated to form Z9-21 Hc (Fig. 3) [78-80]. Other pheromone components include an epoxide and ketone that are produced from Z9-21 Hc by a cytochrome P450 [81,82] and methyl-branched alkanes that are produced by the substitution of methylmalonyl-CoA in place of malonyl-CoA at specific points during chain elongation [83,84]. A novel microsomal fatty acid synthase is involved in production of methyl-branched alkanes in most insects [85-87]. This fatty acid synthase is different from the ubiquitous soluble fatty acid synthase that produces saturated straight chain fatty acids in that it is found in the microsomes and prefers methylmalonyl-CoA. The amino acids valine and isoleucine can provide the carbon skeletons for methylmalonyl-CoA as well as propionate [83]. [Pg.114]

Reed J. R., Quilici D. R., Blomquist G. J. and Reitz R. C. (1995) Proposed mechanism for the cytochrome P450 catalyzed conversion of aldehyde to hydrocarbon in the house fly, Musca domestica. Biochemistry 34, 16221-16227. [Pg.251]

Ahmad S., Kirkland K. E. and Blomquist G. J. (1987) Evidence for a sex pheromone metabolizing cytochrome P-450 monooxygenase in the housefly, Musca domestica L. Arch. Insect Biochem. Physiol. 6, 121-140. [Pg.314]

As noted above, cytochrome b in the mammalian respiratory system is firmly bound to the mitochondrial membrane and cannot be solubilized without using detergents such as cholate. It is thus interesting that a cytochrome b-like pigment, cytochrome b-563, is easily extracted from the larvae and pupae of the housefly, Musca domestica, with a simple salt solution, but it cannot be extracted from the adult flies under the same conditions. The cytochrome is obtained as a crystalline preparation after purification by the chromatography on DEAE-cellulose (78,84). The crystalline cytochrome b-563 has a similar spectral property to mammalian cytochrome b and shows absorption peaks at 563, 530, and 428.5 nm in the reduced state. Contrary to purified mammalian cytochrome b, this cytochrome does not combine with carbon monoxide and exists as monomer species in the solution without detergent. [Pg.564]

Murataliev and Feyereisen have investigated the interaction of recombinant Musca domestica (house fly) P450 reductase with NADPH and the role of the FMN semiquinone in reducing cytochrome The kinetics of the latter process together with EPR spectroscopy revealed that the enzyme has two types of neutral FMN radical. One serves as the catalytic intermediate of cytochrome c reduction while the other is air-stable, reducing cytochrome c 3000 times more slowly. [Pg.234]


See other pages where Musca domestica, cytochrome is mentioned: [Pg.145]    [Pg.228]    [Pg.1059]    [Pg.577]   
See also in sourсe #XX -- [ Pg.564 , Pg.570 , Pg.577 ]




SEARCH



Musca

Musca domestica

© 2024 chempedia.info