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Muramic acid

V-Acetyl muramic acid [NAMA, R-2-(acetylamino)-3-0-(l-carboxyethyl)-2-deoxy-D-glucose] [10597-89-4] M 292.3, m -125°(dec),... [Pg.507]

FIGURE 7.15 Structures of muramic acid aud ueuramiuic acid aud several depictions of sialic acid. [Pg.220]

Muramic acid for 2-amino-3-0-[(/ )-l-carboxyethyl]-2-deoxy-D-glucose. [Pg.84]

Amino-3-0-[(fl)-1-carboxyethyl]-2-deoxy-p-D-glucopyranose (p-muramic acid)... [Pg.85]

The first known 1-carboxyethyl ether of a sugar was 2-amino-3-0-[(/ )-l-carboxyethyl]-2-deoxy-D-glucose or muramic acid (37). It is a component of the polysaccharide moiety of the peptidoglycan in the bacterial cell-wall. It is partially replaced by the mamo isomer, 2-amino-3-6>-[(/ )-l-carboxy-ethyl]-2-deoxy-D-mannose, in the peptidoglycan from Micrococcus lyso-deikticus. [Pg.303]

In the peptidoglycan from some mycobacteria, the muramic acid is A -gly-colylated, not A-acetylated. As already mentioned, ester-linked lactic acid... [Pg.308]

In muramic acid, the 2-hydroxyl group of D-glucose is replaced by an amine group, and a lactic acid group is attached to OH-3. The structure of muramic acid [2-amino-3-0-(D-l-carboxyethyl)-2-deoxy-D-glucopyranose] is given in formula 12. [Pg.112]

Listowsky and coworkers showed that the c.d. of this sugar derivative is due entirely to lactic acid, and confirmed that this chromophore is in the D configuration for muramic acid. N-Acetylmuramic acid, in which the amino group is replaced by an amido group at C-2, has a c.d. spectrum that is roughly a linear combination of the lactic acid in muramic acid and the amide in 2-acetamido-2-deoxy-D-glucose. This indicates that the amide chromophore and the lactic acid chromophore in N-acetylmuramic acid behave independently. [Pg.113]

Chlamydias, however, are bacteria and have been shown to possess a cell wall containing muramic acid (section 2.2.1), to contain ribosomes of the bacterial (prokaryotic) type, to reproduce themselves by binary fission and to be inhibited by antibiotics active against bacteria. [Pg.31]

Burkholderia (formeriy Pseudomonas) cepacia is intrinsically resistant to a number of biocides, notably benzalkonium chloride and chlorhexidine. Again, the outer membrane is likely to act as a permeability barrier. By contrasL Ps. stutzeri (an organism implicated in eye infections caused by some cosmetic products) is invariably intrinsically sensitive to a range of biocides, including QACs and chlorhexidine. This organism contains less wall muramic acid than other pseudomonads but it is imclear as to whether this could be a contributory factor in its enhanced biocide susceptibility. [Pg.269]

B. Hexoses.—Muramic acid 6-phosphate (63), which occurs in the cell walls of bacteria, has now been synthesised, thus confirming the structure of this acid-stable compound. [Pg.142]

A. Fox and R. M. T. Rosario, Quantification of muramic acid, a marker for bacterial peptidoglycan in dust collected from hospital and home air-conditioning filters using gas-chromatography mass spectrometry. Indoor Air-Intemat. J. Air Quality Cl. 4 239 (1994). [Pg.406]

Fox, A. Fox, K. Christensson, B. Harrelson, D. Krahmer, M. Absolute identification of muramic acid at trace levels in human septic fluids in vivo and absence in aseptic fluids. Infect. Immun. 1996, 64, 3911-3955. [Pg.34]

Fox, A. Wright, L. Fox, K. Gas chromatography-tandem mass spectrometry for trace detection of muramic acid, a peptidoglycan marker in organic dust. I. Microbiol. Meth. 1995, 22,11-26. [Pg.34]

Fox, A. Krahmer, M. Harrelson, D. Monitoring muramic acid in air (after alditol acetate derivatization) using a gas chromatography-ion trap tandem mass spectrometer. J. Microbiol. Meth. 1996, 27,129-138. [Pg.34]

Kozar, M. Krahmer, M. Fox, A. Gray, B. M. Failure to detect muramic acid in normal rat tissues but detection in cerebrospinal fluid from patients with pneumococcal meningitis. Infect. Immun. 2000, 68, 4688 1698. [Pg.34]

Shahgholi, M. Ohorodnik, S. Callahan, J. H. Fox, A. Trace detection of underiva-tized muramic acid in environmental dust samples by microcolumn liquid chromatography electrospray-tandem mass spectrometry. Anal. Chem. 1997, 69, 1956-1960. [Pg.35]

Ronkko, R. Pennanen, T. Smolander, A. Kitunen, V. Kortemaa, H. Haahtela, K. Quantification of Frankia strains and other root-associated bacteria in pure cultures and in the rhizosphere of axenic seedlings by high-performance liquid chromatography-based muramic acid assay. Appl. Environ. Microbiol. 1994, 60, 3672-3678. [Pg.198]

Black, G. E. Fox, A. Fox, K. Snyder, A. R Smith, R B. Electrospray tandem mass spectrometry for analysis of native muramic acid in whole bacterial cell hydroslysates. Anal. Chem. 1994, 66,4171 4176. [Pg.253]

See other pages where Muramic acid is mentioned: [Pg.267]    [Pg.296]    [Pg.304]    [Pg.507]    [Pg.549]    [Pg.220]    [Pg.220]    [Pg.279]    [Pg.679]    [Pg.160]    [Pg.177]    [Pg.178]    [Pg.270]    [Pg.388]    [Pg.390]    [Pg.231]    [Pg.149]    [Pg.25]    [Pg.26]    [Pg.238]    [Pg.239]    [Pg.89]    [Pg.7]    [Pg.9]    [Pg.10]   
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D-Muramic acid

IV-Acetyl muramic acid

Muramic acid 8-lactam

Muramic acid bacterial peptidoglycan

Muramic acid derivative

Muramic acid mycobacteria

Muramic acid synthesis

Muramic acid, formation

Muramic acid, glycosides, synthesis

N-Acetyl muramic acid

N-acetyl-D-Muramic acid

Of muramic acid

UDP-muramic acid

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