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Multiplex bead array assay

Another important set of multiplexed assays monitor mRNA transcript levels. The expression level of all the genes involved in a known signal transduction pathway or other selective genes can be monitored simultaneously as a way of following compound effects on a cell. The current technologies for multiple mRNA detection include quantitative reverse transcriptional PCR (qRT-PCR), qNPA (quantitative nuclease protection assays), mass array assay technologies and branched DNA detection on Luminex beads (Panomics). The applications of such multiplexed in vitro and cell-based detection systems should provide more predicative information in hit finding and lead characterisation. [Pg.261]

Morgan E, Varro R, Sepulveda H et al (2004) Cytometric bead array a multiplexed assay platform with applications in various areas of biology. Clin Immunol 110 252-266... [Pg.270]

Morgan, E., R. Varro, H. Sepulveda, J. A. Ember, J. Apgar, J. Wilson, L. Lowe, R. Chen, L. Shivraj, A. Agadir, R. Campos, D. Ernst, and A. Gaur. 2004. Cytometric bead array A multiplexed assay platform with applications in various areas of biology. Clin. Immunol. 110 252-66. [Pg.110]

See other pages where Multiplex bead array assay is mentioned: [Pg.138]    [Pg.138]    [Pg.487]    [Pg.215]    [Pg.217]    [Pg.152]    [Pg.265]    [Pg.583]    [Pg.134]    [Pg.635]    [Pg.946]    [Pg.258]    [Pg.17]    [Pg.21]   
See also in sourсe #XX -- [ Pg.138 ]



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