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Mucin-type carbohydrates

Therkildsen, M. H., Mandel, Y., Thorn, J., Christensen, M., and Dabelsteen, E. 1994. Simple mucin-type carbohydrate antigens in major salivary glands. J. Histochem. Cytochem. 42 1251-1259. [Pg.344]

J. E. Hansen, C. Nielsen, M. Arendrup, S. Olofsson, L. Mathiesen, J. O. Nielsen, H. Clausen, Broadly neutralizing antibodies targeted to mucin-type carbohydrate epitopes of hmnan immunodeficiency virus. J. Virol. 1991, 65, 6461-6467. [Pg.1957]

Kinzy, W. and Schmidt, R. (1987) Glycosylimidates. Part 24. Application of the tricholoroacetimidate method to the synthesis of glycopeptides of the mucin type containing a (3-D-Galp-(l-3)-D-GalpNAcunit. Carbohydr. Res. 164,265-276. [Pg.207]

The functions of the large gel-forming mucins include lubrication of the epithelial surfaces and protection from chemical and physical impact and microbial damage. Bacteria, viruses, and other microbes bind to mucin-type 0-glycans and are trapped by the viscous mucus layer. This may prevent their migration toward the epithelial cell surface and support their removal by ciliary action. Bacteria can also use the carbohydrate moieties of mucins as nutrients. [Pg.317]

Therkildsen MH, Mandel U, Christensen M, Dabelsteen E (1993) Simple mucin-type Tn and sialosyl-Tn carbohydrate antigens in salivary gland carcinomas. Cancer 72 1147-1154... [Pg.262]

Fmoc-threonine tert-butyl ester 7 to afford the desired fully protected Tn-antigen-threonine conjugate 8 . This conjugate provides the following principal advantages for the further extension of the carbohydrate structure in order to cover all mucin-type tumour-associated carbohydrate antigens 1-5 (Scheme 2) ... [Pg.532]

Robbe, C. Capon, C. Flahaut, C. Michalski, J.-C. Microscale analysis of mucin-type O-glycans by a coordinated fluorophore-assisted carbohydrate electrophoresis and mass spectrometry approach. Electrophoresis 2003, 24, 611-621. [Pg.766]

T. Feizi, H. C. Gooi, R. A. Childs, J. K. Picard, K. Uemura, L. M. Loomes, S. J. Thorpe, E. F. Hounsell, Tumour-associated and differentiation antigens on the carbohydrate moieties of mucin-type glycoproteins. Biochem. Soc. Trans. 1984, 12, 591-596. [Pg.1957]


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See also in sourсe #XX -- [ Pg.226 ]




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