High resolution MS

Method abbreviations D-AT-FAAS (derivative flame AAS with atom trapping), ETAAS (electrothermal AAS), GC (gas chromatography), HGAAS (hydride generation AAS), HR-ICP-MS (high resolution inductively coupled plasma mass spectrometry), ICP-AES (inductively coupled plasma atomic emission spectrometry), ICP-MS (inductively coupled plasma mass spectrometry), TXRF (total reflection X-ray fluorescence spectrometry), Q-ICP-MS (quadrapole inductively coupled plasma mass spectrometry)... 

Figure 7.32 shows the identification of an oxidation product of Irganox 1330 by means of APCI-MS. LC-APCI-MS/MS (high-resolution sector field-ion trap hybrid) has also been used for the analysis (elemental composition and structure) of Irganox PS 802 [636]. 

HR-ICP-MS High-resolution inductively coupled ID-TIMS Isotope dilution-inductively coupled... 

Brominated and chlorinated organic flame-retardants can be analysed using either GC-MS or LC-MS. High resolution systems are required to identify the specific isomers. Quantification by bromine or chlorine content is normally achieved using XRF against standards in the same matrix. 

F. Podebrad, M. Heil, S. Leib, B. Geier, T. Beck, A. Mosandl, A. C. Sewell and H. Bohles, Analytical approach in diagnosis of inherited metabolic diseases maple syrup urine disease (MSUD)-simultaneous analysis of metabolites in urine by enantioselective multidimensional capillary gas chromatography-mass spectrometry (enantio-MDGC-MS) ,/. High Resolut. Chromatogr. 20 355-362(1997). 

Comparison of GC- 0.001 [8-MS, high resolution mg 10] mass spectrometry L 1 and high pressure liquid... 

HR-TOP-MS High resolution time of flight-mass spectmm... 

PBO was found to be unstable when subjected to add hydrolysis- When JUC -PBO was refluxed with 1 mol L HCl for 1 hour, a single fluorescent radioactive compound was formed. This compound was isolated by preparative high-performance liquid chromatography (IIPLC) and identified by gas chromatography-mass spectroscopy (GC-MS), high-resolution MS, nuclear magnetic resonance (NMR), and comparison of HPLC retention time with a synthetic standard. 

HREI-MS high-resolution electron-impact mass spectrometry... 

Electron impact (El) and ECNI have been used as ionization methods in low-resolution GC-MS for PCB detection. El is the most selective method. ECNI is more sensitive, but only for molecules which contain five or more chlorine atoms.Occasionally, and depending on substimtion pattern, molecules with four chlorine atoms can also be detected by ECNI-MS. High resolution EI-MS has also been applied for PCB determination, but on a relatively small scale as the costs of using this technique are higher than for using ECD and low-resolution MS (LRMS). 

HR-EI-MS = High Resolution-Electron Impact Ionization-Mass Spectrometry. 

HR-ICP-MS high resolution inductively coupled plasma mass spectrometry(Hy-phenated technique on-line coupled technique (e.g. direct coupling of chromatography and ICP-MS)... 

Other Techniques. A growing technique related to lc/ms and regarded as complementary to it is that of capillary zone electrophoresis/mass spectrometry (cze/ms) (22). Using cze/ms, high resolution separation of water-soluble compounds is accompHshed by the principles of electrophoresis (qv). The sample is then coupled to the mass spectrometer by electrospray ionization (23) or a fast atom bombardment interface (fab) to produce molecular ions (24). Biotechnology applications of cze/ms have great potential (25). 

MSI offers a complementary technique as mass spectrometry can differentiate between various ions on the basis of their molecular weight. Additional selectivity is achieved by utilizing MS", high-resolution mass spectrometry, or orthogonal separation techniques, either separately or combined. Each additional stage of analysis serves to reduce the interfering chemical noise that originates from the tissue without tedious sample preparation. 

HR-ESI-MS High-resolution electrospray ionization mass spectrum... 

CPL Circular Polarized Luminescence HR-MS High-Resolution Mass Spectroscopy... 

Fig. 5.20 (a-d) Time-resolved luminescence and excitation spectra of transparent Canada gros-sular at 300 K with zero delay and different gate and spectral resolution under excitation by 355 nm 19 ms, low resolution (a), 500 ps, low resolution (b), 1 ms, high resolution in visible range (c), 500 ps, high resolution in UV range... 

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