Montreal protocol Subject

No information on potentially susceptible populations was located for HCFC-141b. A structurally related chemical, 1,1,1,2-tetrafluoroethane, has been tested in metered-dose inhalers for the treatment of asthma. Test subjects included adult and pediatric asthma patients as well as individuals with severe COPD. No adverse effects were reported (Smith et al. 1994 Taggart et al. 1994 Ventresca 1995 Woodcock 1995). The structurally related chemicals trichlorofluoromethane (CFC-11) and dichlorodifluoromethane (CFC-12) are presently used in metered-dose inhalers for the treatment of asthma but are phased out under the Montreal Protocol of 1987 (Alexander 1995). Structurally related compounds including 1,1,1-trichloroethane and trichlorofluoromethane were also tested for cardiac sensitization in a dog model with experimentally induced myocardial infarction. In these experiments cardiac sensitization occurred under the same conditions as in healthy dogs (Trochimowicz et al. 1976). 

Trichloroethane was a major solvent, particularly for cold and vapor degreasing. It was phased out for emissive uses in the United States in 1996 because of its ozone depletion potential. The only application left is as chemical precursor for HCFC-141b and HCFC-142b. However, both are subject to phaseout schedule of the Montreal Protocol,... 

Describe any other regulatory information on the substance or mixture that is not provided elsewhere in the SDS (e.g. whether the substance or mixture is subject to the Montreal Protocol, the Stockholm Convention or the Rotterdam Convention ). 

A brief description of the books contents may be helpful. Chapter 1 by M. Okoroafor and K.C. Frisch is an introduction and also covers the subject of foam formation. The chapter includes a discussion of the Montreal Protocol mandating the development of foams with substantially reduced CFC content by 1995. Chapter 2 is a comprehensive discussion of thermosetting foams of all types, with the emphasis on urethane and phenolic foams. The authors, K. Ashida and K. Iwasaki, are recognized authorities in their fields of specialization. This chapter presents extensive discussions of such fields as composites and syntactic foams. There is some overlap between this chapter and topics covered in later chapters, but the treatments are different. 

None of fluoropolymers or their decomposition products poses any threats to the ozone layer. None are subject to any restrictive regulations under the Montreal Protocol and the US Clean Air Act. Reacting HF with chloroform produces the main fluori-nated ingredient of tetrafluoroethylene synthesis CHCIF2. It has a small ozone depleting potential but is excluded from the Montreal Protocol regulation... 

Today, fire-protection halons are subject to international restrictions imposed by the Montreal Protocol on Substances that Deplete the Stratospheric Ozone Layer. Consequently, production of these fire protection agents has been phased out as of January 1,1994. New halon replacements are now available. See NFPA 2001, Clean Agent Fire Extinguishing Systems. 

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