Monoarticular Arthritis

In 0.5% to 3.0% of patients with gonorrhea, the gonococci invade the bloodstream and produce disseminated disease. The usual clinical manifestations of disseminated gonococcal infection are tender necrotic skin lesions, tenosynovitis, and monoarticular arthritis. 

Monoarticular arthritis was produced in the left knee joints of rabbits by using ovalbumin and Freund s complete adjuvant as antigen and adjuvant. Naproxen sodium nanoparticles that were smooth and spherical in shape with a particle size of approximately 5-9 pm were injected into the knee joints. A decrease in the arthritic to normal joints ratios was observed over time. The naproxen sodium nanoparticles were more efficacious than the free drug. 

Includes patients with lesions that had bacterial superinfection, or that made the patient uncomfortable enough to consult a physician. Unusual complications included were a patient with fetal vaccinia, a patient with a melanoma developing in the vaccine scar, and a patient with monoarticular arthritis following vaccination. 

The cyclopeptide 22 (PMX-53, 3D53) was described to be a reeeptor selective C5a antagonist, stable to peptide degradation in blood or gastrie fluid and orally active.PMX-53 was assessed in several pre-clinical efficacy models of monoarticular arthritis, LPS-induced neutropenia, ulcerative colitis, dermal and peritoneal inflammation, and assorted... 

Acute attacks of gouty arthritis are characterized by rapid onset of excruciating pain, swelling, and inflammation. The attack is typically monoarticular... 

Gout is a metabolic disease characterized by recurrent episodes of acute arthritis, usually monoarticular, and is associated with abnormal levels of uric acid in the body, particularly the presence of monosodium urate crystals in synovial fluid. Primary gout is a hereditary disease in which hyperuricemia is caused by an error in uric acid metabolism—either overproduction or an inability to excrete uric acid. Secondary gout refers to those cases in which hyperuricemia is caused by an acquired disease or disorder, such as chronic renal disease, lead poisoning, or myeloproliferative disorders. Gout generally occurs in... 

Similar to the situation in adult rheumatoid arthritis, US has proved to be more sensitive than radiography or clinical examination in the detection of joint effusion and synovial hypertrophy in these patients (Sureda et al. 1994 Lamer and Sebag 2000 El-Miedany et al. 2001). In the knee of children with monoarticular or paudarticular juvenile idiopathic arthritis, quantitative assessment of... 

Cellerini M, Salti S, Trapani S et al (1999) Correlation between clinical and ultrasound assessment of the knee in children with monoarticular or pauciarticular juvenile rheumatoid arthritis. Pediatr Radiol 29 117-123 Chami M, Daoud A, Maestro M et al (1996) Ultrasound contribution in the analysis of the newborn and infant normal and clubfoot a preliminary study. Pediatr Radiol 26 298-302... 

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