Molecularly imprinted polymers selectivity

Karlsson JG, Andersson LI, Nicholls lA. Probing the molecular basis for ligand-selective recognition in molecularly imprinted polymers selective for the local anaesthetic bupivacaine. Anal Chim Acta 2001 435 57-64. 

Farrington, K Magner, E. Regan, F., Predicting the performance of molecularly imprinted polymers, Selective extraction of caffeine by molecularly imprinted solid phase extraction, Anal. Chim. Acta. 2006, 566, 60-68... 

Rachkov, A. McNiven, S. Cheong, S.-H. El Skaya, A. Yano, K. Karube, I., Molecularly imprinted polymers selective for Beta-estradiol, Supramol. Chem. 1998, 9, 317-323... 

Zhou, J. He, X.W. Study of the nature of recognition in molecularly imprinted polymer selective for 2-aminopyridine. Anal. Chim. Acta. 1999, 381, 85-91. 

Why does a molecularly imprinted polymer selectively bind a desired analyte ... 

Table 18.5 Characteristics and figures of merit for automated solid-phase extraction of riboflavin and determination by HPLC-DAD. The procedure proposed by Oliveira et al. (2010) is based on automatic SPE using a renewable column of commercially available molecularly imprinted polymers selective to riboflavin. The solid-phase extraction procedure was coupled online to the reversed phase chromatographic determination, resorting to a monolithic silica C18 column.

Silica CIS or molecularly imprinted polymers selective to riboflavin have been employed as sorbents for solid-phase extraction of riboflavin in foods. 

A.R. Khorrami and A. Rashidpur, Design of a new cartridge for selective solid phase extraction using molecularly imprinted polymers Selective extraction of theophylhne from human serum samples. Biosens. Bioelectron., 25 (3) 647-651,2009. 

The development of highly selective chemical sensors for complex matrixes of medical, environmental, and industrial interest has been the object of greate research efforts in the last years. Recently, the use of artificial materials - molecularly imprinted polymers (MIPs) - with high recognition properties has been proposed for designing biomimetic sensors, but only a few sensor applications of MIPs based on electrosynythesized conductive polymers (MIEPs) have been reported [1-3]. 

Recently, molecularly imprinted polymers (MIPs) have gained attention as new, selective sorbents for chromatography and SPE. The cavities in the polymer... 

The sorbents that are most frequently used in environmental analysis are Cig-silica based sorbents, polymeric sorbents (usually styrenedivinilbenzene) and graphitized carbon. In order to increase the selectivity of these sorbents, immunosorbents (35, 36) have been developed and used with good results, while recently, molecularly imprinted polymers have started be to used (35, 36). 

Tan, ZJ Remcho, VT, Molecular Imprint Polymers as Highly Selective Stationary Phases for Open Tubular Liquid Chromatography and Capillary Elechophoresis, Elechophoresis 19, 2055, 1998. 

Zougagh, M., Valcarcel, M., and Rios, A., Automatic selective determination of caffeine in coffee and tea samples by using a supported liquid membrane-modified piezoelectric flow sensor with molecularly imprinted polymer. Trends Anal. Chem., 23, 399, 2004. 

The selectivity and sensitivity of biosensors are governed by the biocatalyst. Commonly used biocatalysts in biosensors are enzymes [10, 11], antibodies [12, 13], whole cells [14], and artificial receptors such as molecularly imprinted polymers [15, 16],... 

The application of biosensors for process monitoring has been dogged by problems with fouling, selectivity, degrading bioactivity and long-term stability. Recent developments in molecularly imprinted polymers (MIPs) show some promise as synthetic receptors and have been used for this purpose for assays and as HPLC stationary phases. Recent work has shown that MIPs show increased robustness, storage endurance and lower cost compared with biosensors, which... 

Piletsky SA, Terpetschnig E, Andersson HS, Nicholls lA, Wolfheis OS. Application of nonspecific fluorescent dyes for monitoring enantio-selective ligand binding to molecularly imprinted polymers. Fresenius J Anal Chem 1999 364 512-516. 

Sergeyeva TA, Piletsky SA, Brovko AA, Slinchenko EA, Sergeeva LM, El skaya AV. Selective recognition of atrazine by molecularly imprinted polymer membranes. Development of conductometric sensor for herbicides detection. Anal Chim Acta 1999 392 105-111. 

Urraca JL, Hall AJ, Moreno-Bondi MC, Sellergren B. A stoichiometric molecularly imprinted polymer for the class-selective recognition of antibiotics in aqueous media. Angew Chem Int Ed 2006 45 5158-5161. 

IV. CHEMICAL SELECTIVITY THROUGH MOLECULARLY IMPRINTED POLYMER FILMS... 

Molecularly imprinted polymer (MIP) films can be utilized in conjunction with CdSe PL changes to enhance the selectivity of the sensor. MIPs have been developed to mimic the selective binding of molecules to biological substrates, as in... 

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