Modular microfluidic devices

Modular Microfluidics Devices Combining Multidimensional Separations Applications to Targeted Proteomics Analyses of Complex Cellular Extracts... 

Modular Microfluidics Devices Combining Multidimensional Separations 175... 

Microfluidk Assembly, Fig.1 Modular microfluidic board approach (a) illustration of example board technology with electronic and fluidic routing between surface-mounted components and coupling to off-chip devices (b) photograph of example microfluidic board in silicon with live mounted pressure sensors, embedded microchannels, surface electronic routing, and couplers to capillary tubing [2]... 

Beebe DJ, Moore JS, Bauer JM et al (2000) Functional hydrogel structures for autonomous flow control inside microfluidic channels. Nature 404 588-590 Benard WL, Kahn H, Heuer AH, Huff MA (1998) Thin-film shape-memory alloy actuated micropumps. J Microelectromech Syst 7 245-251 Benito-Lopez F, Antonana-Diez M, Curto VF et al (2014) Modular microfluidic valve structures based on reversible thermoresponsive ionogel actuators. Lab Chip 14 3530-3538 Chin CD, Linder V, Sia SK (2012) Commercialization of microfluidic point-of-care diagnostic devices. Lab Chip 12 2118-2134... 

Over the past decade, there has been a broad effort in the scientific community to miniaturize chemical systems via microfluidic platforms. The concept is to construct compact devices with integrated modular functionalities [42]. These micrometer-sized modules can perform functions that are analogous to bench-scale laboratory processes, hence the name, lab-on-a-chip. For making droplets, a lab-on-a-chip microfluidic device could be envisioned to have the following modules ... 

Although the field of microfluidic-MS has bloomed over the past decade, it has not yet received its revolutionary impact. At the root of its overall acceptance lies the requirement of versatile modular components and subsystems, and their integration into complete functional and reliable devices that can be... 

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