Micromixing microheat exchangers

In a detailed process optimization study, the impact of the type of micromixers and process parameters was determined [56]. As a result, a pilot with a Toray Hi-mixer connected to a shell and tube microheat exchanger was constructed. Continuous operation for 24 h was carried out to obtain pentafluorobenzene (PFB) after protonation (92% yield). In this time, 14.7 kg of the product was produced, that is, about 5 t/a. Thus, the industrial-scale production carried out using a batch reactor (10 m3) can be replaced by adding only four microflow systems of the scale investigated. The pilot plant produces 0.5 kg in 6h continuous operation, thus about 730kg/a (see Figure 5.19). The name of the industrial company was not disclosed. 

Figure 3.5 Schematic representation of modular microreactor setup employed for the vitamin A acetate synthesis (1 pressure probe 2 micromixer 3 microheat exchanger 4 capillary reactor with electrical heating 5 thermal liquid inlet for heat exchanger).

Equipment Hewlett Packard 6890 gas chromatograph equipped with a HP-5 0.25 gm, 30 mx 0.32 mm capillary column, a thermostat, three flasks for the reaction educts and products, microreactor setup according to Figure 12.15 with two microheat exchangers, a microreactor, three inlet/outlet modules, and a micromixer. Extra equipment for the experiments in a batch reactor, such as round-bottom flask equipped with a thermometer, a reflux cooler, a dropping funnel, and a mechanical stirrer, are necessary. 

Absorption of CO Micro-bubble column with a static micromixer, reaction platelet and a microheat exchanger Conversion increased by a factor of 2.5 with a residence time of 0.1 s... 

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