Microemulsion characterization procedure

In pharmaceutics, therefore, simple and effective methods and procedures are needed to characterize the interactions of drugs with pharmaceutical excipients (polysaccharides, cyclodextrins, etc.) and vehicle systems (micelles, microemulsions, and liposomes) in order to optimize the load of vehicle systems with the drugs. 

It was soon found that HPH is more effective for the production of submicronsized dispersions of solid lipids than is high-shear mixing or ultrasound [11-13], Dispersions obtained in this way are called SLN. Most SLN dispersions produced by HPH are characterized by an average particle size of around 100 to 200 nm and a low microparticle content. Alternative production procedures were also investigated, including the combination of organic solvents and HPH (HPH/solvent evaporation) [14], the dilution of microemulsions [15,16], and solvent injection [17],... 

Chin AB, Yaacob II (2007) Synthesis and characterization of magnetic iron oxide nanoparticles via w/o microemulsion and Massart s procedure. J Mater Process Technol 191 235-237... 

Preparation of silica nanoparticles via reverse microemulsions is characterized by at least two features common to the above. A common feature is that one of the procedures listed above, namely, addition of an alkoxide (TEOS in this case) into a reverse microemulsion was generally used. Note that the droplets of water were pH-controlled, for example, by the addition of ammonia solution. The second point is the choice of the w value. Here also, it was observed that a low value of w led to no hydrolysis as the water molecules bound themselves to the surfactant molecules and were not available for reaction with the alkoxide. Note on the other hand that the upper limit of the w value is generally determined... 

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