Microbubbles detection methods

Furthermore, it could be shown that the induction of the microbubble-based SAE effect in color Doppler and the rapid blood clearance of nontarge ted USCAs by cells of the reticuloendothelial system within 30-60 min, depending on the dose used, yields a sensitive detection method and a strong signal-to-noise ratio of targeted microcapsules. Moreover, it provides the op-... 

In addition to acoustical methods, which take advantage of the fact that gas nuclei (i.e., stable microbubbles) are elastic bodies and thus absorb sound energy (ref. 4,5,9,25,26,31,32,50), another class of methods for detecting these gas microbubbles that has been employed repeatedly is based on their optical behavior. Specifically, most of these optical methods involve detection of these long-lived microbubbles in water from the light scattered by them (ref. 5,26,59,60,127). 

L-selectin ligand-specific USCA could be a candidate for an indirect method of lymphography for the safe and less-invasive ultrasonic identification of lymph nodes, e.g., when performing a biopsy. Lymph node-targeted microbubbles can be detected easily with any ultrasound device that has color Doppler capabilities. 

Hope Simpson, D., C. T. Chin, et al. 1999. Pulse inversion Doppler A new method for detecting nonlinear echoes from microbubble contrast agents. IEEE Trans Ultras Ferroelectr Freq Control 46 372-382. 

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