Microbiology mycobacteria

C. Raynaud, M. A. Laneelle, R. H. Senaratne, P. Draper, G. Laneelle, M. Daffe, Mechanisms of Pyrazinamide Resistance in Mycobacteria Importance of Lack of Uptake in Addition to Lack of Pyrazinamidase Activity Microbiology 1999, 145, 1359-1367. 

Ratledge C, Ewing M (1996) The Occurrence of Carboxymycobactin, the Siderophore of Pathogenic Mycobacteria, as a Second Extracellular Siderophore in Mycobacterium smegmatis. Microbiology 142 2207... 

Figure 8-11. Influence of adjuvants on the production of antibodies following injection of an immunogen. Schematic view of amounts of antibody produced by rabbits in response to one injection (arrow) of a soluble protein (A) in a dilute salt solution, (B) adsorbed on precipitated alum, or (C) incorporated into a stable water-in-oil emulsion containing mycobacteria (Freund s complete adjuvant). (From B. D. Davis et al.. Microbiology, 2nd ed., Harper and Row, New York, 1973.)...

Every brain biopsy specimen should be handled in such a way that if inflammation is found at surgery, it will be possible to culture the tissue for bacteria, mycobacteria, and fungi and to use special stains, immunostain-ing techniques, and electron microscopy. This author s experience has been that for organisms that grow in vitro, microbiologic culture is preferable to histochemi-cal stains, IHC, or polymerase chain reaction (PCR) assay if sampling of the lesion is uniform. Prior antibiotic treatment or non-uniform sampling of focal infection affects individual cases. 

Michael S. Scherman received his B.S. (Microbiology) and his M.S.B.A (Computer Information Systems) from Colorado State University, CO, USA. He has worked with Dr. Michael R. McNeil at the Mycobacteria Research Laboratories at Colorado State University since 1992, studying the structural aspects of the mycobacterial cell envelope, TB drug development, targeting of key biosynthetic enzymes, and computer modeling of metabolic and enzymatic pathways and structures. 

Kendall SL, Burgess P, Balhana R, Withers M, ten Bokum A, Lott JS, Gao C, Uhia-Castro I, Stoker NG (2010) Cholesterol utilization in mycobacteria is controlled by two TetR-type transcriptional regulators KstR and KstR2. Microbiology-Sgm 156 1362-1371... 

McLean KJ, Marshall KR, Richmond A, Hunter IS, Fowler K, Kieser T, Gurcha SS, Besra GS, Munro AW (2002) Azole antifungals are potent inhibitors of cytochrome P450 mono-oxygenases and bacterial growth in mycobacteria and streptomycetes. Microbiology-Sgm 148 2937-2949... 

K.J. McLean, K.R. Marshall, A. Richmond, l.S. Hunter, K. Fowler, T. Kieser, S.S. Gurcha, G.S. Besra, A.W. Munro, Azole antifungals are potent inhibitors of cytochrome P450 monooxygenases and bacterial growth in mycobacteria and stieptomycetes. Microbiology 148 (2002)... 

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