Methylobacterium organophilum

Xu, H. H., Viebahn, M., and Hanson, R. S., 1993, Identification of methanol-regulated promoter sequences from the facultative methylotrophic bacterium Methylobacterium organophilum XX. J. Gen. Microbiol. 139 7439752. 

Bisseret P., Zundel M., and Rohmer M. (1985) 2jS-Methylho-panoids from Methylobacterium organophilum and Nostoc muscorum, a new series of prokaryotic triterpenoids. Euro. J. Biochem. 150, 29—34. 

Kim BS (2002) Production of medium chain length polyhydroxyalkanoates by fed-batch culture of Pseudomonas oleovorans. Biotechnol Lett 24 125-130 Kim YB, Lenz RW, Fuller RC (1992) Poly(b-hydroxyalkanoate) copolymers containing bromi-nated repeating units produced by Pseudomonas oleovorans. Macromolecules 25 1852-1857 Kim SW, Kim P, Lee HS, Kim IH (1996) High production of poly-beta-hydroxybutyrate (PHB) from Methylobacterium organophilum under potassium limitation. Biotechnol Lett 18 25-30 Kim DY, Kim YB, Rhee YH (1998) Bacterial poly(3-hydroxyalkanoates) bearing carbon-carbon triple bonds. Macromolecules 31 4760-4763... 

The following bacteria recombinant Ralstonia eutropha, Ralstonia eutro-pha, recombinant Escherichia coli, Burkholderia sacchari, Burkholderia cepacia, Azotobacter vinelanddi, Pseudomonas olevorans, Methylobacterium organophilum and Bacillus cereus have more favorable characteristics for industrial scale production. 

The cyclopentenone (35), a chiral precursor for neplanocin, has been prepared from the intermediate (36) obtained by chiral, enzymatic hydrolysis of cis-3.5-diacetoxycyclopenteneBiosynthetic studies have been made on the carbocyclic -pentofuranose (37) which occurs ether-linked to bacteriohopanetetrol in Methylobacterium organophilum. 

ZuNDEL, M., and M. Rohmer Procaryotic triterpenoid. 3. The biosynthesis of 2p-methylhopanoids and 3p-methylhopanoids of Methylobacterium organophilum and Acetobacter pasteurianus ssp pasteurianus. Eur. J. Biochem. 150, 35 (1985). 

Bacterial isoprenoid synthesis - the Rohmer pathway Current biosynthetic evidence indicates that the steps from IPP to isoprenoids in Eubacteria are the same as those in eukaryotes [62-69] (see [70-73] for literature). Especially the incorporation of C-labeled precursors into prokaryotic hopanoids, sterol surrogates in bacterial membranes (see [73] and literature cited therein), or into ubiquinone-8 [70] has revealed that the classic pathway of IPP formation starting from acetyl-CoA via acetoacetyl-CoA, HMG-CoA, MVA, MVA-P, and MVA-PP does not exist in a great variety of bacteria, including E. coli Zymomonas mobilis, Methylobacterium organophilum, Rhodopseudomonas palustris, R. acidophila, Acetobacter aceti ssp. xylinum, but also in the thylakoids of the cyanobacterium Synechocystis sp. [74]. 

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