Methyl thiophosphate

Given the inability to implicate free metaphosphate anion in these studies, Cullis and Rous examined the stereochemical consequence of an alcoholysis reaction (55). When [ 0, 0, 0]P -0-ethyl-P -thiopyrophosphate is treated with methyl iodide in ethanol, the S-methyl derivative rapidly decomposes to form 0-ethyl-S-methyl thiophosphate and ethyl [ 0, 0, 0]phosphate this reaction is thought to proceed via a mechanism involving metaphosphate anion, but, as would be expected on the basis of the observations by Knowles, the stereochemical consequence is nearly quantitative inversion of configuration. In dichloromethane solution, the decomposition of the oxygen chiral substrate yields ethyl [ 0, 0, 0]phosphate that has suffered extensive racemization (approximately 70%). This stereochemical result can be rationalized by the intermediacy of free metaphosphate anion in the absence of nucleophile acceptors. 

Beiner et al. modified a divinylbenzene/A-vinyl pyrrolidone copolymer, containing sulfonic acid groups, with several metal ions. The modified cation-exchange material was used for the extraction of thiols, sulfides, and methyl thiophosphates from water samples, with LODs in the upper ng/1 range after elution with a CSi/toluene mixture and analysis by GC/MS. 

Pure diastereoisomers of 0,0-dinucleoside-0-methyl thiophosphate 36a,b Rp and Sp are readily available (21a,b), and their reaction with sulfuryl chloride fluoride is either fully stereoselective (36a, Rp) or highly selective (36b, Sp) (22). 

Table 12 Stability constant comparisons for the M(PS) complexes formed by Mg, Cd, or Zn and methyl thiophosphate (MeOPS ), uridine 5 -0-thiomonophosphate (UMPS ) or adenosine 5 -0-thiomonophosphate (AMPS ) between the measured stability constants, log (eq. 2), or the stability constants of M(AMPS) corrected for the macrochelate...

Thiirane, 2-keto- — see a-Thiolactones Thiirane, 2-mercaptomethyl-thiophosphate insecticide, 7, 183 tuberculosis inhibition by, 7, 183 Thiirane, 2-methyl-adducts... 

Phosphorothioate 0,0-DiethylO-2-Isopropyl-4-Methyl-6-Pyrimidyl Thiophosphate Diethyl 2-Isopropyl-4-Methyl 6-Pyrimidyl Thionophosphate Alpha-Tox Saralex Spectracide Cherrucal Formula C]2H2iNj03PS. 

Chemical Designations - 5[yn >r m5 MPT 0,0-Dimethyl 0-(p-Nitrophenyl) Phosphorothiorate 0,0-Dimethyl 0-p-Nitrophenyl thiophosphate Parathion-methyl Chemical Formula (CH30)2PS0CjH4N02-P-... 

Chemical Name 2-[(diethoxvphosphinvl)thio]-N,N,N-trimethvlethanaminium iodide Common Name 0,0-diethvl-S-/3-dimethvlaminoethvl thiophosphate methyl iodide Structural Formula ... 

Demeton-S-methyl sulfone (hRf 0-5), dimethoate (h/ f 5-10), demeton-S-metlq (hRf 20-25), triazophos (h/ f 40-45), azinphos-methyl (hRf 40-45), azinphos-ethj (hRf 50-55), malathion (h/ f 60-65), parathion-methyl (hRf 75-80) and parathioo ethyl (h/ f 80-85) yielded yellow to brown chromatogram zones on a light brown bact ground, with thiophosphate insecticides with P = S double bonds appearing as brow zones and those with single P — S bonds as yellow zones. 

Methyl Homolog of Parathion. 0,0-Dimethyl O-p-nitrophenyl thiophosphate... 

A similar reaction of methyl P-D-ribopyranoside (5) with P(NMe2)3 in dioxane gave 2,3,4-bicyclophosphite of P-methyl-D-ribopyranoside, 6a in 90% yield. It was sulfurated and selenated to give the corresponding thiophosphate 6b and selenophosphate 6c in 89 and 81% yields, respectively. Oxidation of 6a with hydrogen peroxide gave cyclic phosphate 6d (92%), whereas its hydrolysis in aqueous... 

Dimethyl phosphorodithioic acid, see Malathion 0,0-Dimethyl phosphorophosphate, see Methoate Dimethyl phosphorothioate, see Malathion, Parathion 0,0-Dimethyl phosphorothioate, see Malathion 0,5-Dimethyl phosphorothioate, see Acephate Dimethyl phosphorothioic acid, see Dimethoate Dimethyl phosphorothionic acid, see Malathion 0,0-Dimethyl phosphorothionic acid, see Malathion Dimethyl sulfide, see Methyl mercaptan Dimethyl thiophosphate, see Malathion Dimethyl thiophosphoric acid, see Malathion Dimethyl triclopyr-aspartate, see Triclonvr Dimethyl triclopyr-glutamate, see Triclopvr... 

Diazinon begins to decompose at a temperature of 100 °C. During distillation procedures at this temperature, <0.5% is decomposed to 2-isopropyl-4-methyl-6-hydroxypyrimidine. When technical diazinon is dissolved in 20% hydrochloric acid, 0,0,0-triethyl thiophosphate is formed (Gysin and Margot, 1958). Above 120 °C, diazinon decomposes and emits toxic fumes of phosphorus, nitrogen, and sulfur oxides (Sax and Lewis, 1987 Lewis, 1990 Wlndholz et al, 1983). 

Treatment of thioindoxyl and its 5-methyl derivative with 0,0-diethyl chlorothiophosphate in the presence of base affords the corresponding 0,0-diethyl-0-(3-benzo[6]thienyl)thiophosphate.606 0,0-... 

Chemical Name 0,0-diethyl 0-2-isopropyl-6-methylpyrimidin-4-yl phosphorothioate 0,0-diethyl-0-(2-isopropyl-6-methyl 4-pyrimidinyl) phosphorothioate 0,0-diethyl 2-isopropyl-4-methylpyrimidinyl-6-thiophosphate Uses nonsystemic insecticide to control flies, aphids and spider mites in soil, fruit, vegetables and ornamentals also... 

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