Methyl salicylate cream

The samples of the formulated creams (19) containing 0.1-0.2 mequiv of alkaloid halides. Salicylic acid, hexochlorophane or methyl salicylate dispersed in cetamacrogol, cetrimide or lanette wax, are dissolved in 35 ml of anhydrous acetic acid (with addition of 5 ml of 3% Hg acetate in the example of alkoids) or dimethylformamide, and are titrated with 0.1 M HCI04 or... 

This cream also contains zinc naphthenate, terpineol, chlorcresol, and methyl salicylate [119-36-8]. The latter has a deeply penetrative effect. It combines... 

Menthol, Methyl Salicylate, and Menthol Cream and Ointment... 

This cream and ointment contain menthol in an alcohol base gel, combinations of methyl salicylate, and menthol in cream and ointment bases, as well as a combination of methyl salicylate, menthol, and camphor in a nongreasy cream base all are suitable for topical application. The varieties include the ointment (methyl salicylate, 18.3% ... 

Methyl Salicylate, Thyme, Pine, and Menthol Foot Cream... 

Absorption of methyl salicylate from the skin depends on the pharmaceutical formulation (i.e. the type and quantity of vehicle), the area covered, the time and site of application, skin blood flow, temperature, and hydration, but in all cases studied the absorption of salicylate has been incomplete. For example, when creams and an ointment containing methyl salicylate were applied to 50 cm areas of the forearm, only 12-20% of the methyl salicylate was absorbed over a 10-hour period, even though the skin was covered. The plasma levels of salicylate were low, at less than 10 mg/1. Nevertheless, substantial amounts of methyl salicylate are absorbed when applied to large areas of skin, especially when covered. 

Perfumes, Flavors, Cosmetics, and Soap. Many naturally occurring esters in essential oils and some synthetic esters are important fragrance and flavor compounds (61,62). They are used in perfumes, flavors, cosmetics, soaps, deteigents, and air fresheners. Benzyl, butyl, ethyl, methyl, and phenyl esters of benzoic acid are used as flavors, perfumes, and food preservatives. Glyceryl 4-aminobenzoate [13644-7] and 2-ethylhexyl 4-dimethylaminobenzoate [21245-02-3] are used in cosmetic sunscreen preparations. Alkyl esters of 4-hydroxybenzoic acid, called parabens, have been used under various names for fungus infections of the skin, and as preservatives in lotions and creams (101). Soap and cosmetic fragrances use large amounts of amyl and benzyl salicylate. Benzyl salicylate [118-58-1] is also used in deodorant sprays. 2-Ethylhexyl salicylate [118-60-5] and 2-ethylhexyl 4-methoxycinnamate [5466-77-3] are used in sunscreen formulations (102). 

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