Methyl-phenyl-carbamic acid

C10H13NO2 methyl-phenyl-carbamic acid ethyl ester 2621-79-6... 

C10H13NO2 (2-methyl-phenyl)-carbamic acid ethyl ester 5255-71-0... 

Reaction of methyl a-L-rhamnopyranoside with triphenylboroxole gave a syrupy boronate ester which was characterized as a crystalline phenyl-carbamate. Removal of the phenylboronic acid residue gave a product identified as methyl a-L-rhamnopyranoside 4-N-phenylcarbamate, since it was identical with that resulting from removal of the ketal group from methyl 2,3-O-isopr opylidene-a-L-rhamnopyranoside 4-N-phenylcarbamate (12). This establishes the structure of the original ester as methyl a-L-rhamnopyranoside 2,3-phenylboronate (24). 

Z-Gly-NHBz[Carbamic acid, [2-oxo-2-[(phenyl-methyl)amino]ethyl]-, phenylmethyl ester] A 94%... 

CN [3-[[2-methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-l-methyl-lH-indol-5-yl]carbamic acid cyclopentyl ester... 

Benzyl frans-1,3-butadiene-1-carbamate 1,3-Butadienecarbamic acid, benzyl ester (8) Carbamic acid, 1,3-butadienyl-, phenyl-methyl ester (9) ( —)... 

Reaction of 4-chloro-6-fluoropyrido[3,4- pyrimidine 59 with [3-methyl-4-(pyridin-3-yloxy)phenyl]amine 60, followed by coupling the formed amine 61 with (3-azabicyclo[3.1.0]hex-6-yl)carbamic acid fi r7-butyl ester, afforded the substituted derivative 62 <2002EPP1249451>. Compound 59 was also reacted with 3-bromoaniline to give the 4-anilino derivative 63 that upon treatment with either methyl- or dimethylamine gave the corresponding 4,6-diamino derivatives 64 (Scheme 2) <1997W09726259, 1995W09519774>. 

CONDENSATION OF METHYL N-PHENYL CARBAMATE WITH SOLID ACID CATALYSTS... 

Fig. 2. Proposed reaction mechanism for methyl N—phenyl carbamate condensation in a liquid acid catalyst (a) and over a sulfonic acid resin(b).

Although these protecting groups may seem bizarre, their value lies in the fact that they can be removed easily by acid-catalyzed hydrolysis under very mild conditions. The sequence of steps is shown in Equation 23-10 and involves proton transfer to the carbonyl oxygen and cleavage of the carbon-oxygen bond by an SN1 process (R = tert-butyl) or SN2 process (R = phenyl-methyl). The product of this step is a carbamic acid. Acids of this type are unstable and readily eliminate carbon dioxide, leaving only the free amine (also see Section 23-12E) ... 

SYNS BAY 39731 BAY 105807 BAYER 39731 CARBAMIC ACID, METHYL-, o-ISOPROPYLPHENYL ESTER CARBAMIC ACID, METHYL-, 2-(l-METHYI ETHYL)PHEKYL ESTER o-CUMENYL METHYL-CARBAMATE ENT 25,670 ETROFOLAN D HYTOX ISOPROCARB ISOPROCARBE o-ISOPROPYI PHENOL METHYLCARBA L TE o-ISOPROPYLPHENYL N-METHYLCARBAMATE 2-ISOPROPYL-PHENYL N-METHYLCYRBAMATE KHE0145 2-(l-... 

DIMETHYLETHOX 0SULFINYL)METHYL)-, 2-(l-METHYLETHOXY)PHENYL ESTER see INE062 CARBAMIC ACID, DIMETHYL-, ester with (m-HYDROXYPHENYL)TRIMETHYLAMMONIUM BROMIDE see PODOOO CARBAMIC ACID, ((2,6-... 

CARBAi nC ACID, METHYL-, o-ISOPROPYLPHENYL ESTER see i nA250 CARBAMIC ACID, METHYL-, 2-(l-METHYLETHYL)PHENYL ESTER see MIA250 CARBAMIC ACID, METHYL-, 3-METHYLPHENYL ESTER (9CI) see MIB750 CARBAMIC ACID, METHYL((4-NITROPHENYL)THIO)-, 2,3-DIHYDRO-2,2-DIMETHYL-7-BENZOFURANYL ESTER see DLH870 CARBAMIC ACID, METHYL-, SPIRO(l,3-BENZODIOXOLE-2,l -CYCLOHEXAN)-4-YL ESTER see SLD550... 

C8H805 spinulosin 85-23-4 25.00 1.3178 2 13735 C8H9N02 carbamic acid, phenyl-, methyl ester 2603-10-3 19.47 1.1446 2... 

Yields are improved in this reaction, relative to phosgene, where the R substituents are small alkyl groups such as methyl or ethyl, although in other cases the reaction was found to be better when phosgene was used. Ring-formed carbamic acid derivatives have been similarly prepared using phenyl chloroformate [806] ... 

Bromination of the compounds 63 using bromine in acetic acid provides the 8-bromo compounds 64. " Although a solution of N-bromosuccinimide in carbon tetrachloride does not brominate the amine 65 (R = H), it does brominate, in an unspecified yield, the carbamate 65 (R = C02Et). The position of substitution was identified as the 8-position on the basis of PMR evidence. There was no evidence of bromination of the methyl group. Bromination of a methyl phenyl compound, described without proof as 66, using bromine in carbon tetrachloride gave the dibromo compound 67. Treatment of 66 with iodine in pyridine gave the pyridinium salt 68, presumably by way of the iodomethyl compound. The orientation of these products remains to be established. 

Synonyms Carbamic acid, methyl-, 2,3-(dimethylmethylenedioxy) phenyl ester 2,2-Dimethyl-1,3-benzdioxol-4-yl N-methylcarbamate 2,2-Dimethyl-1,3-benzodioxol-4-yl methylcarbamate Dycarb Empirical Cn H13NO4... 

Carbamic acid ethyl ester. See Urethane Carbamic acid, homopolymer, octadecyl-ethenyl ester. See Polyvinyl octadecyl carbamate Carbamic acid, N-hydroxymethyl-n-methyldithio-, potassium salt. See Potassium N-hydroxymethyl-N-methyIdithiocarbamate Carbamic acid, (mercaptoacetyl) methyl-, ethyl ester, S-esterwith 0,0-diethyl phosphorodithioate. See Mecarbam Carbamic acid, methyl-, 2,3-(dimethylmethylenedioxy) phenyl ester. See Bendiocarb... 

Carbamic acid, methyl-, o-isopropylphenyl ester Carbamic acid, methyl-, 2-(1-methylethyl) phenyl ester. See 2-lsopropylphenyl N-methylcarbamate... 

Synonyms Carbamic acid, methyl-, o-isopropy I phenyl ester Carbamic acid, methyl-, 2-(1-methylethyl) phenyl ester o-Cumenyl methylcarbamate Isoprocarb o-Isopropylphenol methylcarbamate o-lsopropylphenyl N-methylcarbamate Methyl carbamic acid-o-cumenyl ester 2-(1-Methylethyl) phenyl methylcarbamate MIPC Phenol, o-isopropyl-, methylcarbamate Phenol, 2-(1-methylethyl)-, methylcarbamate Empiricai C11H15NO2... 

Synonyms B 37344 Bay 9026 Bay 37344 Bayer 37344 3,5-Dimethyl-4-(methyl-thio)phenyl methylcarbamate 3,5-Dimethyl-4-methylthiophenyl A -methylcarbamate Draza ENT 25726 H 321 Mercaptodimethur Mesurol Methyl carbamic acid 4-(meth-ylthio)-3,5-xylyl ester 4-Methylmercapto-3,5-dimethylphenyl A -methyl carbamate 4-Methylthio-3,5-dimethylphenyl methyl carbamate 4-Methylthio-3,5-xylyl isomethylcar-bamate Metmercapturon NA 2757 OMS 93. 

Chlorophenoxy)phenyl)-l,l-dimethylurea, see Chloroxuron 7V -(4-(4-Chlorophenoxy)phenyl)-7V,7V-dimethylurea, see Chloroxuron 1 -(4-Chlorophenoxy)-3,3 -(1,2,4-triazol- l-yl)butan-2-one, see Triadimefon 7V-(((4-Chlorophenyl)ainino)carbonyl)-2,6-difluorobenzamide, see Diflubenzuron (3-Chlorophenyl)carbamic acid 1-methylethyl ester, see Chlorpropham tran5-5-(4-Chlorophenyl)-7V-cyclohexyl-4-methyl-2-oxo-3-thiazolidinecarboxainide, see Hexythiazox... 

Methyl-2-oxo-l,3-dithiolo[4,5-6]quinoxaline, see Quinomethionate (Methylphenyl)carbamic acid 3-((methoxycarbonyl)amino)phenyl ester, see... 

A large-scale cyclization reaction of carbamates with functionalized butenoates, starting from carbamates prepared without phosgene, for the efEdent preparation of 3-(substituted phenyl)-5-isopropylidene-l,3-oxazolidine-2,4-dione derivatives (azaladones) having potent herbicidal adivity, has been described in a patent application [240]. By reacting an N-(substituted phenyl)carbamate 312 with a 2-hydroxy-3-alkenoic acid ester (for example, ethyl 2-hydroxy-3-methyl-3-butenoate) or a 3-alkoxy-2-hydroxyalkanoic add ester, at 210 °C for 15 h, azaladone 313 was formed in 71.5% yield. 

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