2- Methyl- carbamate

The reaction is applicable to the preparation of amines from amides of aliphatic aromatic, aryl-aliphatic and heterocyclic acids. A further example is given in Section IV,170 in connexion with the preparation of anthranilic acid from phthal-imide. It may be mentioned that for aliphatic monoamides containing more than eight carbon atoms aqueous alkaline hypohalite gives poor yields of the amines. Good results are obtained by treatment of the amide (C > 8) in methanol with sodium methoxide and bromine, followed by hydrolysis of the resulting N-alkyl methyl carbamate ... 

This approach is compHcated by the fact that the isocyanate is produced via the thermolytic cleavage of the methyl carbamate. Reactions with the unconverted carbamate caimot be prevented. Much effort has been focused on improving the selectivity of the latter step. 

Pesticides are further subdivided into classes of compounds. Historically, insecticides included the organochlorine, methyl carbamate, and organophosphate classes of pesticides. Herbicides comprise about 10—12 principal classes of compounds. Within each class of pesticide there may be several hundred active ingredients. 

Methyl Carbamate 5. 9-Fluorenylmethyl Carbamate 8. 2,2,2-Trichloroethyl Carbamate 11. 2-Trimethylsilylethyl Carbamate 16. 1,1-Dimethylpropynyl Carbamate 20. 1-Methyl-1-phenylethyI Carbamate 22. 1-Methyl-l-(4-biphenylyl)ethyl Carbamate 24. 1,1 -Dimethy 1-2-haloethyl Carbamate 26. l,l-Dimethyl-2-cyanoethyl Carbamate 28. r-Butyl Carbamate... 

Originally, p-tolylsulfonyldiazomethane was prepared by passing an ethereal solution of its precursor, ethyl i 7-nitroso-iV -(j3-toly]8ulfonyI-methyl)carbamate, slowly through a column of alumina, This procedure, which results in yields about 10% higher, is convenient only for small-scale preparations, up to a maximum of 5 g. of p-tolylsulfonyl-diazomethane. The present modification is due to Middelbos, ... 

Determination of Aldicarb and other N-methyl carbamates in Waters (by HPLC or Confirmation of total Aldicarb residues and other N-methyl carbamates in waters by GC), 1994... 

K2CO3, MeOH, 67% yield. These conditions were used to cleave a methyl carbamate from an aziridine. ... 

Di- -butyl[9-(10,10-dioxo-10,10,10,10-tetrahydrothioxanthyl)]methyl Carbamate (DBD-Tmoc-NR2) ... 

After having been cooled it is washed three times in water, three times in a 5% solution of caustic soda, and then another three times in water. The solution in xylene is dried over sodium sulfate and the xylene is completely distilled off in vacuo. Thus 11.0 parts of hexa-methylene-bis-(N-methyl carbamic acid-3-pyridyl ester) are obtained. 

Chemical Name [[(8 )-1,6-dimethylergolin-8-yl] methyl] carbamic acid phenylmethyl ester Common Name Methyl-N-carbobenzoxy-dihydro-lysergamine Structural Formula ... 

The reaction of amides with half equiv. of BTMA Bf3 and one equiv. of DBU in dichloromethane-methanol at room temperature gave N-substituted acylureas in fairly good yields (Fig. 34). Furthermore, in the presence of a large excess of methanol, the reaction of amides with one equiv. of BTMA Bt3 and two equiv. of DBU in dichloromethane gave methyl carbamates as main products (Fig. 35). In these reactions, we assumed that in the presence of DBU, intermediary isocyanates react with excess of amides to afford acylureas, and react with excess of methanol to afford methyl carbamates (ref. 42). 

Fig. 35. Preparation of methyl carbamates from amides with BTMA Br3...

C9H13NO 104-63-2) see Indeloxacine Phenmetrazine 7-(2-benzylaminoethyl)theophylline (C15H19N5O2 22680-61-1) see Fenetylline Theodrenaline benzyl [(2R,35)-3-amino-2-hydroxy-4-phenylbutyl](2-methylpropyl)carbamate monohydrochloride (C22H3[C1N20j 160232-11-1) see Amprenavir 2-benzylamino-l-(4-methoxyphenyl)propane (C17H21NO 43229-65-8) see Fenoterol Formoterol benzyl [3-[(2-aminophenyl)carbamoyl]propyl]methyl> carbamate... 

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