Carbamic acid phenyl ester

A solution of 3.1 g of (2-benzoyl-4-chlorophenyl-carbamoylmethyl)carbamic acid benzyl ester in 30 cc of 20% hydrobromic acid in glacial acetic acid was stirred for 45 minutes at room temperature. On addition of 175 cc of anhydrous ether, a gummy solid precipitated. After several minutes the ether solution was decanted. The resultant 5-chloro-2-gly-cylaminobenzophenone was not isolated, but about 155 cc of ether was added to the residue and after chilling in an ice bath, 10% sodium hydroxide was added until the mixture was alkaline. The ether layer was then separated, washed twice with water and dried over sodium sulfate. After filtration, the ether solution was concentrated to dryness in vacuo. The residue was crystallized from benzene to yield 7-chloro-5-phenyl-3H-1,4-benzodiazepin-2(1 H)-one. 

CN [3-[[2-methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-l-methyl-lH-indol-5-yl]carbamic acid cyclopentyl ester... 

Amino-4-(4-fluoro-benzylamino)-phenyl]-carbamic acid ethyl ester, C16H18FN302, MW 303.33, [150812-12-7]... 

CARBAMIC ACID, DIMETHYL, ester with (m-HYDROXYPHENYL)TRIMETHYLAMMONIUM BROMIDE EUSTIGMIN BROMIDE (m-HYDROXY-PHENYL)TRIMETHYLAMMONIUM BROMIDE DIMETHYLCARBAMATE 3-HYDROXYPHENYL-TRIMETHYLAMMONIUM BROMIDE DIMETHYL-CARBAMIC ESTER KIRKSTIGMINE BROMIDE LEOSTIGMINE BROMIDE NEOESERINE BROMIDE... 

C8H805 spinulosin 85-23-4 25.00 1.3178 2 13735 C8H9N02 carbamic acid, phenyl-, methyl ester 2603-10-3 19.47 1.1446 2... 

Carbamic acid ethyl ester. See Urethane Carbamic acid, homopolymer, octadecyl-ethenyl ester. See Polyvinyl octadecyl carbamate Carbamic acid, N-hydroxymethyl-n-methyldithio-, potassium salt. See Potassium N-hydroxymethyl-N-methyIdithiocarbamate Carbamic acid, (mercaptoacetyl) methyl-, ethyl ester, S-esterwith 0,0-diethyl phosphorodithioate. See Mecarbam Carbamic acid, methyl-, 2,3-(dimethylmethylenedioxy) phenyl ester. See Bendiocarb... 

Davies and co-workers also applied a ring-closing metathesis strategy in their preparation of constrained p-amino acid derivatives. Their work employed a chiral auxiliary, S -(l-phenyl-ethyl)-carbamic acid benzyl ester, to achieve the desired P-amino acid derivatives in a stereoselective fashion. Treatment of diene precursors 46 and 48 with 4 mol % of 3 in refluxing dichloromethane provided the corresponding carbocyclic P-amino acid derivatives 47 and 49 in 85 and 35% yield, respectively, with greater than 95% diastereoselectivity in both cases. The diminished yield in the case of 49 is presumably due to sterics effects. 

C10H13NO2 methyl-phenyl-carbamic acid ethyl ester 2621-79-6... 

ClgHi3NO, 1-Phenyl-2-methyl-3-isoquinolone, 40B, 254 CigHi BrN, 1-Phenyl-3-methylisoquinoline hydrobromide, 41B, 331 Ci6Hii,BrN02, 2-(4 -Bromophenyl)-4,6-dimethoxyindole, 46B, 253 Cl gHi i,BrN303, (5-Benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl ester hydrobromide, 46B, 254... 

C9H11 N02 phenyl-carbamic acid ethyl ester 101-99-5... 

Z-Gly-NHBz[Carbamic acid, [2-oxo-2-[(phenyl-methyl)amino]ethyl]-, phenylmethyl ester] A 94%... 

Benzyl frans-1,3-butadiene-1-carbamate 1,3-Butadienecarbamic acid, benzyl ester (8) Carbamic acid, 1,3-butadienyl-, phenyl-methyl ester (9) ( —)... 

Reaction of 4-chloro-6-fluoropyrido[3,4- pyrimidine 59 with [3-methyl-4-(pyridin-3-yloxy)phenyl]amine 60, followed by coupling the formed amine 61 with (3-azabicyclo[3.1.0]hex-6-yl)carbamic acid fi r7-butyl ester, afforded the substituted derivative 62 <2002EPP1249451>. Compound 59 was also reacted with 3-bromoaniline to give the 4-anilino derivative 63 that upon treatment with either methyl- or dimethylamine gave the corresponding 4,6-diamino derivatives 64 (Scheme 2) <1997W09726259, 1995W09519774>. 

Preparation of tertiary alkyl esters of carbamic acid by the ammonolysis of mixed phenyl alkyl carbonates to yield alkyl carbamate and phenol [24, 40, 41]. 

The condensation of an aldehyde, benzyl carbamate, and triphenyl phosphite, first described by Oleksyszyn et al., 25,26 affords a direct route to a-aminoalkylphosphonates 4 that are conveniently protected for subsequent reactions (Scheme 4). Since dealkylation of the quaternary phosphonium intermediate 3 is not possible in this case, formation of the pen-tavalent product 4 presumably involves activation of the solvent and formation of phenyl acetate. This method is useful for the synthesis of aliphatic and aromatic amino acid analogues. However, monomers with more elaborate side chains are often incompatible with the reaction conditions. The free amine can be liberated by treatment with HBr/AcOH or by hydrogenolysis after removal of the phenyl esters. The phosphonate moiety can be manipulated by ready exchange of the phenyl esters in alkaline MeOH and activation as described in Section 10.10.2.1.1. Related condensations with other trivalent phosphite derivatives have been reported. 27-30 ... 

N-(phenyl methylene)- (622-29-7), 65, 140 2-Methyl-2-butene 2-Butene, 2-methyl- (513-35-9), 65, 159 Methyl carbamate Carbamlc acid, methyl ester (598-55-0), 65, 159 METHYL 4-CHLORO-2-BUTYNOATE 2-BUTYN0IC ACID, 4-CHL0R0-, METHYL ESTER (41658-12-2), 65, 47... 

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