Methyl ferf-butyl ketone

This ketone is unique amongst those studied in that it apparently exhibits no region of negative temperature coefficient of the rate and no cool flames have been observed [45]. The pressure—time curves were similar to those of methyl iso-propyl ketone at 310 °C, the reaction accelerating smoothly and then stopping suddenly [46]. Analyses of the combustion products have been made at various stages of the reaction at 270, 310 and 350 °C. Carbon monoxide, carbon dioxide, hydrogen peroxide, iso-butene-1 2-oxide, methanol, methyl ethyl ketone and acetaldehyde were all detected, and towards the end of the reaction iso-butene and methane were also formed. 

At 400 °C, the latter two hydrocarbons were major products, while the formaldehyde and hydrogen peroxide concentrations passed through sharp maxima which coincided with the maximum rate of pressure rise. 

At 400 °C the iso-butene yield is enhanced, but the carbon dioxide yield is not the iso-butene does not therefore appear to be formed from the iert-butyl radical produced in (3), and Anderson and Hoare [46] suggest another reaction 

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Mosher and LaCombe (1950) reduced methyl ferf-butyl ketone... 

The surprisingly-rapid reactions observed for ketones containing ferf-butyl groups (such as methyl terf-butyl ketone and di-terf-butyl ketone) have two implications ... 

Special care must be taken for water soluble analytes such as ketones, alcohols, etc. It is advisable to purge them at an elevated temperature of 80°C. Despite the boiling points and vapor pressure of fuel oxygenated compoimds (such as methyl-ferf-butyl ether, ethyl-terf-butyl ether, ethyl-butyl alcohol, etc.), frequent problems are encountered as a result of their high solubility in water. Thus the method performance must be checked. The use of an appropriate analytical column and heating to 80°C rather than ambient temperature are proposed modifications in EPA Method 5030C. 

Tlie bifunctional sulfenyl chloride 213 was obtained by chlorination of 144 in good yield, although excessive chlorination led to the saturated compound 214 (94CB533). A series of compounds 215-220 were obtained from 213 by reactions with secondary amines ferf-butyl methyl ketone hexane-2,4-dione 2,6-dimethylcyclohexanone diethyl malonate and acetylacetone, respectively. 

KETONE, ferf-butyl phenyl [1-Propanone, 2,2-dimethyl-l-phenyl-], 55, 122 Ketone, methyl ethyl- [2-Butanone, 55, 25 KFTONES, acetylenic [Ketones, ethynic]... 

Action of Diethylamine on Decomposition of Ethyl tert-Butyl Peroxide. The rate of decomposition of ethyl ferf-butyl peroxide is decreased by adding diethylamine (Figure 7), and the yield of products is altered (Table II). Again, the yield of methane is increased at the expense of ethane and f erf-butyl alcohol is increased at the expense of acetone. Ethanol and acetaldehyde are formed in considerably greater amounts. The yields of carbon monoxide and methyl ethyl ketone are decreased. 

Suitable inert solvents include methyl ethyl ketone, benzene, ethylbenzene and toluene. Suitable initiators include peresters and peroxycarbonates such as ferf-butyl perbenzoate, ferf-butyl peroxy isopropyl carbonate, fcrf-butyl peroctoate, tert-butyl peroxy isonon-... 

Be this as it may, hthium attempts to bind to several bonding partners, and the structural consequences for the enolates of a ketone, an ester, and an amide are shown in Figure 10.2 In contrast to the usual notation, these enolates are not monomers at all The heteroatom that carries the negative charge in the enolate resonance form is an excellent bonding partner, such that several such heteroatoms are connected to every hthium atom. Lithium enolates often result in tetramers if they are crystallized in the absence of other hthium salts and in the absence of other suitable neutral donors. The hthium enolate of ferf-butyl methyl ketone, for example, crystallizes from THF in the form shown in Figure 10.3. 

For demonstration, the SEC behavior of different polymethacrylates is given in Fig. 6. On silica gel as the stationary phase and methyl ethyl ketone as the eluent, all polymethacrylates elute in the SEC mode. The calibration curves of elution volume vs. molar mass for poly(methyl methacrylate) (PMMA), poly(ferf-butyl methacrylate) (PtBMA), poly( -butyl methacrylate) (PnBMA) and po-ly(decyl methacrylate) (PDMA) reflect the inability of the system to separate dif-... 

To prove this hypothesis a suitable substrate, l-diazo-3-methyl-3-[(E)-phenyldiazenyl]butan-2-one (42) was used. Methyl 2-(2-arylhydrazino)-2-methylpropanoate (39) reacting with a bulky Grignard reagent like isopropyl magnesium bromide gives 4,4-dimethyl-2-phenyl-l,2-diazeti-din-3-one 40 (87TL6577). Oxidation with ferf-butyl hypochlorite converts diazetidinone 40 into 2-methyl-2-(phenyldiazenyl)propanoyl chloride 41, which upon treatment with diazomethane affords the desired diazo ketone 42 (Scheme 8) (98ACE2229). 

Schlaad, H., Muller, A. H. E., Kolshom, H., and Kruger, R.-P., Mechanism of Anionic Polymerization of (Meth)acrylates in the Presence of Aluminium Alkyls. 3. MALDI-TOF-MS Study on the Vinyl Ketone Formation in the Initiation Step of Methyl Methacrylate with ferf-Butyl Lithium, Polymer Bull., 35, 177, 1995. 

Sample Solution (a) The only a hydrogens in ferf-butyl methyl ketone are those of the methyl group attached to the carbonyl. Only a hydrogens are acidic enough to be removed by hydroxide. None of the hydrogens of the ferf-butyl group are a hydrogens. 

Regarding the phosphonium ylide derivative III-86, there are three publications of the Wittig olefination of carbonyl compounds with indolylmethyl phosphonium ylide derivatives [206-208]. In Scheme 4.59, two examples are highlighted the reaction of ferf-butyl 3-((bromotriphenylphosphoranyl)methyl)-17/-indole-l-car-boxylate (III-87) with a ketone [206], and the reaction of 5-bromo-l-butyl-3-((iodotriphenylphosphoranyl)methyl)-l//-indole (III-88) with an aldehyde [207]. 

A solii. of ferf-butyl methyl ketone in GGI4 treated with BFs-etherate, ice-cooled, ketene introduced, then the solvent removed in vacuo whereby the intermediate / -lactone rearranges exothermically to the y-lactone y ,, y,y-tetramethyl-y-butyrolactone. Y 67%. F. e. s. G. Metzger, D. Borrmann, and R. Wegler, B. 100,1817 (1967). 

In Table 9 the results of the preparation of (5)-cyanohydrins starting from both aldehydes and ketones with HCN and recombinant HbHNL as catalyst are summarized [9,29]. The reactions with HbHNL were performed normally in a biphasic system consisting of a concentrated aqueous enzyme solution and an organic solvent not miscible with water, e.g., ferf-butyl methyl ether. It must be noted that the reactions and optical yields in the HbHNL-catalyzed cyanohydrin formation (Table 9) were achieved by using the 10-fold higher amount of enzyme, in comparison to MeHNL-catalyzed reactions (Tables 7 and 8) (see notes to Tables 7 and 9). 

Ketones with the general formula 043(012) CO(CH2)jjCH3, where m = 1, = 4, which contain a, a -secondary C-H bonds and cy-cloheptanone, which contains a, [3 and y secondary C-H bonds, 4-4-methyl or 4-tert-butyl cyclohexanone with y-ferf-C-H bond,... 

Scheme 9.82. The Stobbe condensation between diphenyl ketone (benzophenone) and diethyl succinate (diethyl butanedicarboxylate) in the presence of potassium ferf-butoxide [K0C(CH3)3] and in 2-methyl-2-propanoi (fert-butyl alcohol) solvent. The condensation is shown as occurring via a cyclic intermediate. (See Stobbe, H. Chem Ber., 1893,26, 2312, and, for a particularly insightful use, see Johnson, W. S. McCloskey, A. L. Dunnigan, D. A. J. Am.Chem.Soc., 1950, 72,514.

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