Metabolism cooperativity

Pellerin, L. Lactate as a pivotal element in neuron-glia metabolic cooperation. Neurochem. Int. 43 331-338, 2003. 

Flodstrom, S., L. Wamgard, S. Ljungquist, and U.G. Ahlborg. 1988. Inhibition of metabolic cooperation in vitro and enhancement of enzyme altered foci incidence in rat liver by the pyrethroid insecticide fenvalerate. Arch. Toxicol. 61 218-223. 

Kurata M, Hirose K, Umeda M. 1982. Inhibition of metabolic cooperation in Chinese hamster cells by organochlorine pesticides. Gann 73 217-221. 

Elmore, E., Korytynski, E.A. Smith, M.P. (1985) Tests with the Chinese hamster V79 inhibition of metabolic cooperation assay. Prog. Mutat. Res., 5, 597-612 Environmental Protection Agency (1984) Guidelines establishing test procedures for the analysis of pollutants under the Clean Water Act. Final Rule and Interim Final rale and Proposed Rule. Fed. Reg., 49, 43234-43312... 

Kombrast, D.J., Barfknecht, T.R. Ingram, P. (1984) Effect of di(2-ethylhexyl)phthalate on DNA repair and lipid peroxidation in rat hepatocytes and on metabolic cooperation in Chinese hamster V-79 cells. J. Toxicol, environ. Health, 13, 99-116 Kurata, Y., Kidachi, F., Yokoyama, M., Toyota, N., Tsuchitani, M. Katoh, M. (1998) Subchronic toxicity of di(2-ethylhexyl)phthalate in common marmosets lack of hepatic peroxisome proliferation, testicular atrophy, or pancreatic acinar cell hyperplasia. Toxicol. Sci., 42, 49-56... 

Loprieno, N., Boncristiani, G, Forster, R. Goldstein, B. (1985) Assays for forward mutation in Schizosaccharomycespombe strain PL Prog. Mutat Res., 5, 297-306 Lutz, W.K. (1986) Investigation of the potential for binding of di(2-ethylhexyl) phthalate (DEHP) to rat liver DNA in vivo. Environ. Health Perspect., 65, 267-269 Malcolm, A.R. Mills, L.J. (1989) Inhibition of gap-jnnctional intercellular communication between Chinese hamster lung fibroblasts by di(2-ethylhexyl) phthalate (DEHP) and trisodinm nitrilotriacetate monohydrate (NTA). Cell Biol. Toxicol., 5, 145-153 Malcolm, A.R., Mills, L.J. McKeima, E.J. (1983) Inhibition of metabolic cooperation between Chinese hamster V79 cells by tnmor promoters and other chemicals. Ann. N.Y. Acad. Set, 407, 448-450... 

Scott, J.K., Davidson, H. Nelmes, A.J. (1985) Assays for inhibition of metabolic cooperation between mammalian cells in culture. In Ashby, J., de Serres, F.J., Draper, M., Ishidate, M., Jr, Margolin, B.H., Matter, B.E. Shelby, M.D., eds, Progress in Mutation Research, Volume 5, Evaluation of Short-Term Tests for Carcinogens. Report of the International Programme on Chemical Safety s Collaborative Study on in vitro assays, Amsterdam, Elsevier Science, pp. 613-618... 

Murray AW, Fitzgerald DJ Tumor promotors inhibit metabolic cooperation in cocultures of epidermal and 3T3 cells. Biochem Biophys Res Commun 1979 91 395-401. 

Umeda, M., Noda, K. Tanaka, K. (1985) Assays for inhibition of metabolic cooperation by a microassay method. Prog. Mutat. Res., 5, 619-622... 

Chen, T.H., Kavanagh, T.J., Chang, C.C. Trosko, J.E. (1984) Inhibition of metabolic cooperation in Chinese hamster V79 cells by various organic solvents and simple compounds. Cell Biol. Toxicol., 1, 155-171... 

Malcolm, A.R., Mills, L.J. McKenna, E.J. (1985) Effects of phorbol myristate acetate, phorbol dibutyrate, ethanol, dimethylsulfoxide, phenol, and seven metabolites on phenol on metabolic cooperation between Chinese hamster V79 lung fibroblasts. Cell biol. Toxicol., 1, 269-283... 

Awogi, T., Itoh, T. Tsushimoto, G. (1986) The effects of benzene and its derivatives on metabolic cooperation (Abstract). Mutat. Res., 164, 236... 

Chinese hamster cells Inhibition of metabolic cooperation... 

Malcolm AR, Mills LJ. 1983. Inhibition of metabolic cooperation between Chinese hamster V79 cells by tumor promoters and other chemicals. Am NY Acad Sci. 407 488-450. 

Fig. 13.3. Metabolic cooperation between BHK21/C3 cells. Growth of BHK-HPRT-and BHK-TK- cells separately and in mixed (1 1) culture, in medium containing hypoxanthine, aminopterin and thymidine (HAT medium). HPRT = hypoxanthine phosphoribosyl transferase TK = thymidine kinase. (Reproduced from Pitts, 1971, with kind permission of the author and publisher.)...

Trosko, J. E., Dawson, B., and Chang, C. C. (1981). PBB inhibits metabolic cooperation in Chinese hamster cells in vitro. Its potential as a tumor promoter. Environ Health Perspect 37, 179—182. 

Mercier, T., Honikman-Leban, E., Chaumontet, C., Martel, R, and Shahin, M. M. (1993). Studies on the modulating effects of retinoic acid and retinol acetate using dye transfer and metabolic cooperation assays. Fundam Appl Toxicol 21, 270-276. 

Evidence has accumulated in support of the hypothesis (78,79) that DDT inhibits metabolic cooperation (84,107) thereby causing a loss of control on cell proliferation. DDT was shown to inhibit cell-to-cell communication between primary cultures of hepatocytes and an established adult rat liver epithelial cell, 6-thioguanlne resistant strain (84). Recently, DDT was compared with a phorbol ester and quercetin in the same system and the phrobol ester and DDT were found to be synergistic Indicating that they may act by different pathways (107). The well established promotor action of DDT appears to be consistent with its capacity to inhibit cell-to-cell communication. 

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