Metabolic Syndrome high blood glucose

Any relationship between obesity and stroke is likely to be confounded by the positive association of obesity with hypertension, diabetes, hypercholesterolemia and lack of exercise, and the negative association with smoking and concurrent illness. Nevertheless, stroke is more common in the obese, and abdominal obesity appears to be an independent predictor of stroke (Suk et al. 2003). The constellation of metabolic abnormalities including central obesity, decreased high density lipoprotein, elevated triglycerides, elevated blood pressure and impaired glucose tolerance is known as the metabolic syndrome and is associated with a three-fold increase risk of type 2 diabetes and a two-fold increase in cardiovascular risk (Eckel et al. 2005 Grundy et al. 2005). 

Glucose-6-phosphate Dehydrogenase Over Activation. The role of G6PDH over activation has recently been implicated in the development of S)mdrome X , also known as metabolic syndrome . Metabolic syndrome is a cluster of conditions that greatly increases the risk of cardiovascular disease (CVD) and type 2 diabetes (T2D). Currently, millions of individuals around the world are affected by this disease. Patients with this disease concurrently show insulin resistance, visceral obesity or belly fat, atherogenic dyslipidemia (comprises a triad of increased blood concentrations of small, dense low-density lipoprotein-LDL, decreased high-density lipoprotein-HDL and increased triglycerides) and hypertension. 

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