1-Naphthyl mercapturic acid

Roubal et al. (8) applied TLC to the separation and identification of metabolites of l c-iabeled naphthalene administered to coho salmon fingerlings via intraperitoneal injection. 1-Naphthol, a dihydrodiol, mercapturic acid, 1-naphthyl glucuronic acid and a glycoside/sulfate fraction were identified in brain, liver, gall bladder, and muscle 1-naphthol, a dihydrodiol, and 1-naphthyl glucuronic acid were the only metabolites found in heart. 

Coho salmon naphthalene 1-naphthol 1-naphthyl-glucuronate 1-naphthyl-glucoside mercapturic acid 1-naphthyl sulphate 1,2-dihyroxy-1,2-dihydro-naphthalene... 

When mercapturic acids were administered to rats, the recovery of the original material was quite variable. Marsden and Young (1958) found only 33% of a-naphthylmercapturic acid was excreted unchanged by rats. This was less than half of the neutral sulfur of the urine and it seems probable some naphthyl-L-cysteine was excreted. Parke and Williams (1951) found 45% of a dose of phenylmercapturic acid was excreted unchanged and 14% as phenylcysteine,... 

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