Mercaptopropionyl glycine

Agents that contain SH-groups such as cysteine or 2-mercaptopropionyl glycine were able to neutralize feverfew inhibitory activity on platelets [52]. Further, the same study demonstrated a dramatic reduction in the number of acid-soluble SH-groups, both by feverfew and parthenolide. These effects... 

Glutathione is a tripeptide, which is a principle intracellular defense against oxidative stress. Models ofits interaction with VO(IV) were prepared using sulfhydryl-containing pseudopeptides such N-(2-mercaptopropionyl)glycine (H 3 mpg)... 

Shibasaki T, Murai S, Kodama K, Nakano H, Ishimoto F, Sakai O. A case of nephrotic syndrome due to alpha-mercaptopropionyl glycine in a patient with familial cysti-nuria. Nippon Jinzo Gakkai Shi 1990 32(8) 933-7. 

Meunier L, Krause E, Guillot B, Bameon G, Sany J, Meynadier J. Pemphigus induit par I alpha-mercaptopropionyl-glycine. [Pemphigus induced by alpha-mercaptopropionylgly-cine.] Presse Med 1988 17(13) 647. 

T. Miki, M.V. Cohen and J.M. Downey, Failure of N-2-mercaptopropionyl glycine to reduce myocardial infarction after 3 days of reperfusion in rabbits, Basic Res. Cardiol. 94(3), 180-187 (1999). 

Pre-treatment with the reactive oxygen scavenger N-(2-mercaptopropionyl)-glycine completely inhibited monocyte chemotactic protein-1 induction by dog cardiac venules in reperfused infarcts (Lakshminarayanan et al. 2001). In situ hybridisation localised monocyte chemotactic protein-1 message to small venular endothelium in ischaemic areas without myocyte necrosis. Immunohisto-chemical staining demonstrated reperfusion-dependent nuclear translocation of c-Jun and NF-xB (p65) in small venular endothelium, only in the... 

SERS data gave evidence for U02 ON A-(2-mercaptopropionyl)glycine-modified silver colloid. IR data have been reported for uranyl acetate and oxalate in KBr matrices.U02 species are adsorbed on to colloidal silver and Ag20 surfaces. The VsU02 mode shifts to lower wavenumber on adsorption. 

Thiola (Of-mercaptopropionyl glycine) is a new drug developed to replace D-penicill-amine in the treatment of cystinuria. The drug was used in 9 patients for treatment and post-operative prophylaxis. Dosage was 200—1,000 mg daily for 3-42 months with an average of 13 months. Seven out of 9 patients reacted favourably to the treatment, but the number is too small to allow definitive conclusions. 

Remien, A., Kallistratos, G. and Burck-hatdt, P. (1975) Treatment of cystinuria with Thiola (a-mercaptopropionyl glycine). Europ. Urol, 1, 227. 

Limited thermal data are available for other gold(I) mercaptide compounds. Gold(I) bomyl mercaptide decomposes between 134 and 240°C [14], gold(I) di-mercaptosuccinic acid (Au-dmsa) starts to decompose at 194°C [26], and gold(I)-N-(2-mercaptopropionyl)glycine is reported to melt at 230°C, with decomposition [24],... 

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