Meningitis Pseudomonas aeruginosa

Meropenem (Merrem IV) inhibits syndiesis of die bacterial cell wall and causes die deadi of susceptible cells. This drug is used for intra-abdominal infections caused by Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, and odier susceptible organisms Meropenem also is effective against bacterial meningitis caused by Neisseria meningitidis, Streptococcus pneumoniae, and Hemophilus influenzae. 

Optimal antibiotic therapies for gram-negative bacillary meningitis have not been fully defined. Meningitis caused by Pseudomonas aeruginosa is initially treated with ceftazidime or cefepime, piperacillin + tazobactam, or meropenem plus an aminoglycoside, usually tobramycin. 

In a report of a patient who was successfully treated with intrathecal colistin for post-neurosurgical ventriculitis due to Pseudomonas aeruginosa there were no nervous system adverse reactions [102 ]. In reviewing the literature, the authors noted that instillation of colistin into the nervous system may cause meningitis or ventriculitis, but they did not report the incidence. 

Streptococcus sanguis Escherichia coli K99 Escherichia coli, S-fimbriae (newborn human meningitis) Bordetella bronchiseptica Pseudomonas aeruginosa Helicobacter (Campylobacter) pylori... 

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