Membrane bioprocess engineering

Groot WJ, Soedjak HS, Donck PB, ban der Fans RGJM, Luyben KCAM, and Timmer JMK, Butanol recovery from fermentations by hquid-hquid extraction and membrane solvent extraction. Bioprocess Engineering 1990, 5, 203-216. 

Tietjen, K. G. Hunkier, D. Matem, U. "Differential Response of Cultured Parsley Cells to Elicitors from Two Non-pathogenic Strains of Fungi, 1. Identification of Induced Products as Coumarin Derivatives" Eur. ]. Biochem. 1983,131, pp 401-407. Devereux, N. Hoare, M. Duimill, P. "Membrane Separation of Protein Precipitates Unstirred Batch Studies" Biotech, and Bioeng. 1986, 28, pp 88-96. Mateus, M. Cabral, J. M. S. "Recovery of 6-a-methylprednisolone from biotransformation medium by tangential flow filtration" In Bioprocess Engineering. 1989, Springer Verlag, (in press). 

Ripperger, S. and Schulz, G., Microporous Membranes in Biotechnical Pcpx> CA xon, Bioprocess Engineering, 1 43-49 (1986)... 

First applications of membrane reactors can be foimd in the field of bioprocess engineering using whole cells in fermentations or enzymatic bioconversions [6, 7]. Most of these processes use polymeric membranes, as temperatures seldomly exceed 60 °C. The development of inorganic membrane materials (zeolites, ceramics and metals) has broadened the application potential of membrane reactors towards the (petro) chemical industry [8]. Many of these materials can be applied at elevated temperatures (up to 1000°C), allowing their application in catalytic processes. 

A case of application in chemical and bioprocess engineering is the use of pressure to promote the permeation of certain species in a membrane. This is the principle behind Reverse Osmosis. 

Sisak, C., Nagy, E., Burfeind, E., Schugerl, K., 2000. Technical aspects of separation and simultaneous enzymatic reaction in multiphase enzyme membrane reactors. Bioprocess Engineering 23,503-512. 

Park, B. G., Lee, W. G., Chang, Y. K., Chang, H. N. (1999). Long-term operation of continuous high cell density culture of Saccharomyces cerevisiae with membrane filtration and on-line cell concentration monitoring. Bioprocess Engineering, 21, 97—100. 

Cabasso, I., Encyclopedia of Polymer Science and Engineering, Vol. 9, p. 509. Mulder, M.H.V., Nature of Membranes , in Howell, J.A., Sanchez, V and R.W. Field (eds.). Membranes in Bioprocessing. Theory and applications, Chapman Hall, London, 1993... 

Cheryan, M. (1992) Membrane technology in food and bioprocessing. In Advances in Food Engineering, (eds Singh, R.P. and Wirakartakusumah, M.A.). CRC Press, London, pp. 165-179. 

Chen, R.R. (2007) Permeability issues in wholecellular membrane engineering. Apjd. Microbiol. Biotechnol., 74, 730-738. 

Cano, A., Moschou, E. A., Daunert, S., Coello, J. Palet, C. (2006). Optimization of the xylan degradation activity of monolithic enzymatic membranes as a function of their composition using design of experiments. Bioprocess and Biosystems Engineering, 29, 261-268. 

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