Engineering bioprocess

Committee on Bioprocess Engineering, National Research Council, Putting Biotechno/ogy to Work Bioprocess Engineering, National Academy of Sciences, Washington, D.C., 1992, pp. 2—22. 

Doran, P.M., Bioprocess Engineering Principles . Academic Press, New York, 1995. 

Shuler, M.L. and Kargi, F., Bioprocess Engineering, Basic Concepts . Prentice-Hall, New Jersey, 1992. 

Fermentation broths are complex, aqueous mixtures of cells, comprising soluble extracellular, intracellular products and any unconverted substrate or unconvertible components. Recovery and extraction of product is important in bioprocess engineering. In particular separation is a useful technique it depends on product, its solubility, size of the process, and product value. Purification of high-value pharmaceutical products using chromatography such as hormones, antibody and enzymes is expensive and difficult to scale up.1 Tire necessary steps to follow a specific process depend on the nature of the product and the characteristics of the fermentation broth. There are a few steps for product recovery the following processes are discussed, which are considered as an alternative for product recovery from fermentation broth. 

Bayer AG, Process Development/Bioprocess Engineering, D-42096 Wuppertal, Germany E-mail hans-juergen.henzler.hh bayer-ag.de... 

Div. of Environmental and Chemical Engineering and Dept, of Bioprocess Engineering, Chonbuk National University, 664-14 Duckjin-Dong, Jeonju, Jeonbuk 561-756,... 

A.Bono, B.Ariffin, M.Rajin S.H. Keman, Proceeding of the Meraational Conference On Chemical Bioprocess Engineering, Volume 2 (2003) 1001. 

Shuler ML and Kargi F (2002) Bioprocess Engineering, 2nd Edition, Prentice Hall... 

Chapters 1-4 serve as an introduction to emerging biocatalysts, modern expression hosts, state of the art of directed evolution, high-throughput screening, and bioprocess engineering for industrial applications. 

Department of Chemical Engineering and BioProcess Engineering Research Center, Korea Advanced Institute of Science and Technology, 373-1 Kusong-dong, Yusong-gu, Taejon 305-701, Korea,... 

Bioprocess engineering, scaleup to a functional prototype of technical scale... 

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