Media procedure guidelines

Last but not least there is an urgent need to "harmonize" or "standardize" all these procedures so that improved interlaboratory comparisons can be achieved. Such procedures include, cell isolation, growth substrates, cell culture media including the mode of medium application. A first initiative in this direction has been taken by ECVAM (European Center for the Validation of Alternative Methods, a section of the European Commission Institute for Health and Consumer Protection) by founding a task force dealing with the creation of guidelines for "Good Cell Culture Practice" [247, 248]. 

Procedures vary according to type of sample and medium. Guidelines are supplied with the medium or pre-packed column. 

There are currently no comprehensive guidelines or codes for the design and installation of small and medium-sized electrolyzers. Considering future operation mainly by private users, international guidelines for quality criteria, safety requirements, licensing procedures, and testing methods should be implemented [57]. 

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