MCF7 breast cancer cells

The present work aimed to investigate the estrogenicity of industrial pollutants discharged into water resources by studying modifications in the cell kinetics of MCF7 breast cancer cell cultures and effects on the... 

VI. Vignon, F., Capony, F., Chambon, M., Freiss, G., Garcia, M., and Rochefort, H., Autocrine growth stimulation on the MCF7 breast cancer cells by the estrogen-regulated 52K protein. Endocrinology 118, 1537-1545 (1986). 

Moffat, G.J., A.W. McLaren, and C.R.Wolff (1994). Involvement of Jun and Fos proteins in regulating transcriptional activation of the human pi class glutathione S-transferase gene in multidrug-resistant MCF7 breast cancer cells. J. Biol. Chem. 269 16397-16402. 

MDR1 resistent cell line of MCF7 breast cancer cell... 

Rsu-1 results in elevation of p21CIP and inhibits anchorage- 120. independent growth of MCF7 breast cancer cells. Breast Cancer Res. Treat. 2000 61 69-78. 

Figure 7.9 Data-dependent microfluidic LC-MS-MS analysis of a protein fraction prepared from the MCF7 breast cancer cell line (SCX fraction eluted with 50-70 mM NaCl). Conditions 2 cm long x 50 pm deep channel, Zorbax SB-( I S c/, — 5 pm packing material, 2 x 200 pumping channels ( 1.5 pm deep), 2 x 100 valving channels, LC eluent NH4HCO3 (15mM) in H20 CH3OH (40 60) at pH 8, flow rate 60-70 nLmin-1. (Reprinted with permission from ref. 33).

Chen, Y. S. Huang S. Lin-Shiau J. Lin. Bowman-Birk inhibitor abates proteasome function and suppresses the proliferation of MCF7 breast cancer cells through accumulation of MAP kinase phosphatase-1. Carcinogenesis, 200S, 26, 1296—1306. 

Hydrophobically modified glycol chitosan (HGC) with 5p cholanic acid has been extensively studied both in vitro and in vivo. This polymer was developed as a new Cremophor EL-free alternative carrier systems for docetaxel [74] and paclitaxel. Physical characteristics of the nanoparticules such as size, hydrophobic core, and stability depend on the degree of 5-p cholanic acid substitution. The maximum loading content of paclitaxel into HGC nanoparticles was 10 wt% and the loading efficiency was above 90% [120]. Cytotoxicity studies on MCF7 breast cancer cells showed that HGC nanoparticles were less toxic than Cremophor EL, and allowed a higher dose of paclitaxel administration. The survival rate of mice that received 50 mg/kg paclitaxel in HGC nanoparticles increased substantially compared to 20 mg/kg PTX in Cremophor EL-ethanol solutions [120]. 

Ozek, N.S. et al. (2010) Characterization of microRNA-125b expression in MCF7 breast cancer cells by ATR-FUR spectroscopy. Analyst, 135, 3094—3102. 

Table 4.3 IC50 values (nM) for inhibition of HDACs from HeLa nuclear extracts and individual HDAC isoforms (where available) by thiol forms of members of the FK228 family of depsipeptide natural products and growth inhibition of the MCF7 breast cancer cell line by the prodrug natural products (data taken from ref. 68, 74 and 75).

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