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Murine asthma mast cells

Kim YS.KoHM, Kang Nl.etal Mast cells play a key role in the development of late airway hyperresponsiveness through TNF-oi in a murine model of asthma. Eur J Immunol 2007 37 1107-1115. [Pg.66]

With these differences in mind, we review some of the important findings identified using mouse models of human asthma with specific emphasis on the role of mast cells and IgE. We present published studies and our own data that investigate the role of mast cells and IgE in murine models of allergic inflammation. Finally, we attempt to interpret and reconcile the disparate murine data and put them in context with recent human trials using an anti-IgE antibody. [Pg.105]

I. Evidence Indicating a Lack of Involvement of Mast Cells in Murine Asthma Models... [Pg.105]

Despite these caveats, the data obtained from certain murine asthma models demonstrate significant modulatory effects of both mast cells and IgE on allergic inflammation. Notably, these models include mice specifically bred to produce... [Pg.118]

Tepper J, et al. The role of mast cells and IgE in murine asthma (abstr). Asthma... [Pg.123]

Kobayashi T, et al. An essential role of mast cells in the development of airway hyperresponsiveness in a murine asthma model. J Immunol 2000 164(7) 3855-3861. [Pg.123]

See other pages where Murine asthma mast cells is mentioned: [Pg.62]    [Pg.439]    [Pg.241]    [Pg.482]    [Pg.311]    [Pg.296]    [Pg.103]    [Pg.424]    [Pg.435]    [Pg.26]    [Pg.103]    [Pg.105]    [Pg.106]    [Pg.118]    [Pg.119]    [Pg.120]   
See also in sourсe #XX -- [ Pg.105 , Pg.112 , Pg.113 ]



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