Mass spectrometry 252Cf plasma

B. Sundqvist and R. D. Macfarlane. 252Cf-Plasma Desorption Mass Spectrometry. Mass Spectrom. Rev., 4(1985) 421-460. 

Hunt, J.E., MacFarlane, R.D., Katz, J.J., and Dougherty, R.C. 1981. High-energy fragmentation of chlorophyll a and its fully deuterated analog by 252Cf plasma desorption mass spectrometry. J. Am. Chem. Soc. 103 6775-6778. 

Sundqvist, B. and Macfarlane, R. D., 19 8 5, 252Cf-plasma desorption mass spectrometry, Mass Spectrom. Rev. 4 421-460. 

The book is organized into three sections. The first contains the most recent views on fundamental aspects of particle bombardment. Discussions of 252Cf plasma desorption and laser desorption mass spectrometry have been included for comparison. The second section addresses the issues involved in instrument design, covering work on liquid metal and FAB ion guns. The last part presents representative applications of these bombardment methods. 

The analytically important features of Fourier transform ion cyclotron resonance (FT/ICR) mass spectrometry (1) have recently been reviewed (2-9) ultrahigh mass resolution (>1,000,000 at m/z. < 200) with accurate mass measurement even 1n gas chromatography/mass spectrometry experiments sensitive detection of low-volatility samples due to 1,000-fold lower source pressure than in other mass spectrometers versatile Ion sources (electron impact (El), self-chemical ionization (self-Cl), laser desorption (LD), secondary ionization (e.g., Cs+-bombardment), fast atom bombardment (FAB), and plasma desorption (e.g., 252cf fission) trapped-ion capability for study of ion-molecule reaction connectivities, kinetics, equilibria, and energetics and mass spectrometry/mass spectrometry (MS/MS) with a single mass analyzer and dual collision chamber. 

Plasma-desorption mass spectrometry (PDMS) also allowed location of the acyl functions. Thus, 252Cf-PDMS of LOS V in M. kansasii gave27 molecular-weight-associated ions at mlz 2499. The major acylating function of the intact LOS was determined to be a 2,4-dimethyltetradecanoate. Addition of three of these fatty acyl residues to the oligosaccharide portion gave a mass of 2476 daltons. Thus, the ion at mlz 2499 must be equivalent to [M + Na]+, and therefore LOS V must be a tri-O-acyl-undecasaccharide. However, exact location of the acyl functions was not obtained in this way. 

Cf-plasma desorption time-of-flight mass spectrometry. Int. J. Mass Spectrom. Ion Phys. 1976, 21, 81-92. 

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