Marine algae herpes

M. E. R. Duarte, D. G. Noseda, M. D. Noseda, S. Tulio, C. A. Pujol, and E. B. Damonte, Inhibitory effect of sulfated galactans from the marine alga Bostrichia montagnei on herpes simplex virus replication in vitro, Phytomedicine, 8 (2003) 53—58. 

In order to find new sources of antiviral agents with different mechanisms of action, extracts of marine algae from all over the world were assayed for anti-HSV activity. The first screening of 89 types of seaweed collected from British Columbia, Canada and Korea for antiviral activity was reported by Kim et al. [66]. Analipus japonicus was the most potent anti-herpes algae. Extracts from 13 types of Korean seaweed previously shown to contain antiviral activity were investigated in more detail in order to learn their mechanism of action [14]. Four species, Enteromorpha linza, Colpomenia bullosa, Scytosiphon lomentaria and Undaria pinnatifida were active against HSV. In experiments to determine the site of action of these antiviral extracts, the predominant activity was virucidal (i.e., direct inactivation of virus particles) rather than inhibition of virus replication. 

Park, H. J., Kurokawa, M., Shiraki, K., Nakamura, N., Choi, J. S., and Hattori, M. (2(X)5). Antiviral activity of the marine alga Symphyocladia latiuscula against herpes simplex virus (HSV-1) in vitro and its therapeutic efficacy against HSV-1 infection in mice. Biol. Pharm. 

Whitley, R. J. and Roizman, B. (2001). Herpes simplex virus infections. Lancet 357,1513-1518. Zandi, K., Salimi, M., and Sartavi, K. (2007). In vitro antiviral activity of the red marine alga from Persian gulf, Gracilaria scdicornia against herpes simplex virus type 2. /. Biol. Sci. 7,... 

Hatch, M.T, Ehresmann, D.W., and Deig, E.F. (1979) Chemical characterization and therapeutic evaluation of anti-herpes virus polysaccharides from species of Dumontiaceae, in Marine Algae in Pharmaceutical Science (eds H.A. Hoppe, T. Levring, and Y. Tanaka). Walter de Gruyter, Berlin, New York, pp. 343-363. 

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