Lysergic acid diethylamide -like drugs

Hallucinogen-like activity of these compounds as potential bioisosteres of T,T-dimethyltryptamine was evaluated in the two-lever drug discrimination paradigm using LSD- and DOI-trained rats (LSD = lysergic acid diethylamide DOI = 2,5-dimethoxy-4-iodoamphetamine). 

Hallucinogenic mushrooms, containing psilocybin, and lysergic acid diethylamide (LSD) are extremely common recreational drugs. Like ecstasy and related drugs, LSD has a strong... 

Like other club drugs—including ecstasy (MDMA), ketamine, GHB (gamma-hydroxy butyrate), methamphetamine, and LSD (d-lysergic acid diethylamide)—Rohypnol is easily accessible and relatively inexpensive. Often, users who intentionally take the drugs to get high at rave parties or elsewhere may not even know what they have taken or been given, which can make it difficult for medical professionals to treat them if they overdose or have a reaction. 

For decades researchers have looked at whether intoxication with certain drugs could mimic the signs and symptoms of schizophrenia. Amphetamines increase dopamine release and can induce some positive symptoms like paranoia. Lysergic acid diethylamide (LSD) affects 5-HT receptors but tends to induce visual perception changes and not frank hallucinations. Phencyclidine (PCP), however, induces a state in healthy controls that seems very similar to schizophrenia. This includes thought disorder and negative symptoms... 

Q7 Other conditions which may present similar symptoms include drug-induced psychosis such as one brought on by lysergic acid diethylamide, or LSD, or amphetamine, personality disorder or affective psychosis. In older patients dementia may present with schizophrenia-like symptoms, but these patients usually have significant memory deficits, which do not occur in schizophrenia. 

Lysergic acid diethylamide (LSD)-like drugs, including mescaline, psyilocybin, and psilocin ... 

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